Technology Process of C21H22N2O2
There total 7 articles about C21H22N2O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); sodium tert-pentoxide; XPhos;
In
1,2-dimethoxyethane;
at 150 ℃;
Microwave irradiation;
DOI:10.1021/co2000289
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / tetrahydrofuran / 0 °C
2: n-butyllithium / toluene / -78 - 20 °C
3: 2-nitrobenzenesulfonyl hydrazide; triethylamine / dichloromethane / 20 °C
4: tris-(dibenzylideneacetone)dipalladium(0); sodium tert-pentoxide; XPhos / 1,2-dimethoxyethane / 150 °C / Microwave irradiation
With
tris-(dibenzylideneacetone)dipalladium(0); n-butyllithium; 2-nitrobenzenesulfonyl hydrazide; sodium tert-pentoxide; sodium hydride; triethylamine; XPhos;
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; toluene;
4: Buchwald-Hartwig cross coupling reaction;
DOI:10.1021/co2000289
- Guidance literature:
-
Multi-step reaction with 3 steps
1: n-butyllithium / toluene / -78 - 20 °C
2: 2-nitrobenzenesulfonyl hydrazide; triethylamine / dichloromethane / 20 °C
3: tris-(dibenzylideneacetone)dipalladium(0); sodium tert-pentoxide; XPhos / 1,2-dimethoxyethane / 150 °C / Microwave irradiation
With
tris-(dibenzylideneacetone)dipalladium(0); n-butyllithium; 2-nitrobenzenesulfonyl hydrazide; sodium tert-pentoxide; triethylamine; XPhos;
In
1,2-dimethoxyethane; dichloromethane; toluene;
3: Buchwald-Hartwig cross coupling reaction;
DOI:10.1021/co2000289
