C₂₃H₂₂F₇NO₂

Base Information

• Chemical Name: C₂₃H₂₂F₇NO₂
• CAS No.: 609850-67-1
• Molecular Formula: C₂₃H₂₂F₇NO₂
• Molecular Weight: 477.422
• Mol file: 609850-67-1.mol

Synonyms:

Chemical Property of C₂₃H₂₂F₇NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₂F₇NO₂

There total 5 articles about C₂₃H₂₂F₇NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H22F7NO2 → C23H22F7NO2 (609850-67-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 0 °C

2: potassium carbonate / dimethyl sulfoxide / 0.25 h / 140 °C / Microwave irradiation

With potassium carbonate; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.bmcl.2011.09.018

Reference yield:

C8H3F6NO5S → C23H22F7NO2 (609850-67-1)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(l) iodide; dichlorobis(tri-O-tolylphosphine)palladium; triethylamine / acetonitrile / 20 °C

2: iron; acetic acid / 0.5 h / 60 °C

3: dichloromethane / 0 °C

4: potassium carbonate / dimethyl sulfoxide / 0.25 h / 140 °C / Microwave irradiation

With copper(l) iodide; dichlorobis(tri-O-tolylphosphine)palladium; iron; potassium carbonate; acetic acid; triethylamine; In dichloromethane; dimethyl sulfoxide; acetonitrile; 1: Sonogashira coupling;

DOI:10.1016/j.bmcl.2011.09.018

Reference yield:

C23H20F7NO4 → C23H22F7NO2 (609850-67-1)

Guidance literature:

Multi-step reaction with 3 steps

1: iron; acetic acid / 0.5 h / 60 °C

2: dichloromethane / 0 °C

3: potassium carbonate / dimethyl sulfoxide / 0.25 h / 140 °C / Microwave irradiation

With iron; potassium carbonate; acetic acid; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.bmcl.2011.09.018

upstream raw materials:

2-nitro-3-(trifluoromethyl)phenol

3-Trifluoromethylphenol