6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide

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Chemical Name:6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide
CAS No.:1569352-20-0
Molecular Formula:C₃₉H₃₂BrClN₆O₇
Molecular Weight:812.076
Hs Code.:

6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide

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Chemical Property of 6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide

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Technology Process of 6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide

There total 3 articles about 6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₃H₂₈BrClN₂O₅

: 126799-84-6
1-azidomethyl-3-nitrobenzene

: 1569352-20-0
6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide

Guidance literature:: With copper diacetate; sodium L-ascorbate; In ethanol; at 20 ℃; for 6h;
DOI:10.1021/co4001259

Reference yield:

: 1761-61-1
5-bromosalicyclaldehyde

: 1569352-20-0
6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 10 h / 20 °C

2: ethanol / 8 h / 20 °C

3: copper diacetate; sodium L-ascorbate / ethanol / 6 h / 20 °C

With copper diacetate; sodium L-ascorbate; In ethanol; 1: |Knoevenagel Condensation / 2: |Ugi Condensation / 3: |Huisgen Cycloaddition;
DOI:10.1021/co4001259

Reference yield:

: 2199-87-3
6-bromocoumarin-3-carboxylic acid

: 1569352-20-0
6-bromo-N-(4-chlorophenyl)-N-(2-(cyclohexylamino)-1-(2-((1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-oxoethyl)-2-oxo-2H-chromene-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 8 h / 20 °C

2: copper diacetate; sodium L-ascorbate / ethanol / 6 h / 20 °C

With copper diacetate; sodium L-ascorbate; In ethanol; 1: |Ugi Condensation / 2: |Huisgen Cycloaddition;
DOI:10.1021/co4001259