3-((tert-Butyldiphenylsilyl)oxy)propan-1-ol

Base Information

• Chemical Name: 3-((tert-Butyldiphenylsilyl)oxy)propan-1-ol
• CAS No.: 127047-71-6
• Molecular Formula: C19H26O2Si
• Molecular Weight: 314.5
• DSSTox Substance ID: DTXSID40437295
• Nikkaji Number: J1.075.186A
• Wikidata: Q82252775
• Mol file: 127047-71-6.mol

Synonyms:127047-71-6;3-((tert-Butyldiphenylsilyl)oxy)propan-1-ol;1-Propanol, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-;3-[tert-butyl(diphenyl)silyl]oxypropan-1-ol;3-(tert-butyldiphenylsiloxy)propanol;3-[(TERT-BUTYLDIPHENYLSILYL)OXY]PROPAN-1-OL;C19H26O2Si;SCHEMBL440160;DTXSID40437295;NZAGJZSHKTYYMN-UHFFFAOYSA-N;CFA04771;MFCD28992011;3-(tert-Butyldiphenylsiloxy)-1-propanol;AS-69609;3-(tert-Butyldiphenylsilyloxy)propan-1-ol;-3Tert-Butyldiphenylsilyl)Oxy)Propan-1-Ol;3-(tert-butyl-diphenylsilyloxy)-1-propanol;CS-0036970;3-{[tert-butyl(diphenyl)silyl]oxy}propan-1-ol;W11536;3-(tert-butyl-diphenyl-silanyloxy)-propan-1-ol

Chemical Property of 3-((tert-Butyldiphenylsilyl)oxy)propan-1-ol

Chemical Property:

• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 314.170206602
• Heavy Atom Count: 22
• Complexity: 294

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCCO

Technology Process of 3-((tert-Butyldiphenylsilyl)oxy)propan-1-ol

There total 4 articles about 3-((tert-Butyldiphenylsilyl)oxy)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butylchlorodiphenylsilane (58479-61-1) + trimethyleneglycol (504-63-2) → 3-(tert-butyldiphenylsilyloxy)propan-1-ol (127047-71-6)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 25 ℃; Heating;

DOI:10.1016/S0040-4020(99)00844-3

Reference yield: 97.0%

tert-butylchlorodiphenylsilane (58479-61-1) + trimethyleneglycol (504-63-2) → 3-(tert-butyldiphenylsilyloxy)propan-1-ol (127047-71-6)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 60 ℃; for 35.25h;

DOI:10.1002/chem.201202553

Reference yield: 94.0%

C25H40O2Si2 → 3-(tert-butyldiphenylsilyloxy)propan-1-ol (127047-71-6)

Guidance literature:

With cerium(III) chloride; sodium iodide; In acetonitrile; for 24h; Ambient temperature;

DOI:10.1055/s-1998-1601

upstream raw materials:

tert-butylchlorodiphenylsilane

trimethyleneglycol

Downstream raw materials:

(3-Azido-propoxy)-tert-butyl-diphenyl-silane

1-(t-butyldiphenylsilyloxy)-3-iodopropane

Agel 416

NPS 019