1-[(9Z)-1-Oxo-9-octadecenyl]piperidine

Base Information

• Chemical Name: 1-[(9Z)-1-Oxo-9-octadecenyl]piperidine
• CAS No.: 4637-46-1
• Molecular Formula: C₂₃H₄₃NO
• Molecular Weight: 349.601
• NSC Number: 60357
• DSSTox Substance ID: DTXSID001339616
• Nikkaji Number: J2.021.342F
• ChEMBL ID: CHEMBL1222428
• Mol file: 4637-46-1.mol

Synonyms:4637-46-1;N-oleoylpiperidine;NSC60357;CHEMBL1222428;SCHEMBL11545683;DTXSID001339616;NSC-60357;1-(piperidin-1-yl)octadec-9-en-1-one;(Z)-1-(1-piperidyl)octadec-9-en-1-one;1-[(9Z)-1-Oxo-9-octadecenyl]piperidine;(9Z)-1-(1-Piperidinyl)-9-octadecen-1-one

Chemical Property of 1-[(9Z)-1-Oxo-9-octadecenyl]piperidine

Chemical Property:

• Vapor Pressure: 2.12E-09mmHg at 25°C
• Boiling Point: 480.7°C at 760 mmHg
• Flash Point: 194.5°C
• Density: 0.904g/cm³
• XLogP3: 8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 15
• Exact Mass: 349.334464995
• Heavy Atom Count: 25
• Complexity: 331

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCCCC=CCCCCCCCC(=O)N1CCCCC1
• Isomeric SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)N1CCCCC1

Technology Process of 1-[(9Z)-1-Oxo-9-octadecenyl]piperidine

There total 5 articles about 1-[(9Z)-1-Oxo-9-octadecenyl]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

piperidine (110-89-4) + (Z)-9-octadecenoyl chloride (112-77-6) → (Z)-1-(piperidin-1-yl)octadec-9-en-1-one (4637-46-1)

Guidance literature:

With indium; In acetonitrile; at 20 ℃; for 3h;

DOI:10.1016/j.tetlet.2004.01.114

Reference yield: 92.0%

piperidine (110-89-4) + cis-Octadecenoic acid (112-80-1,2027-47-6) → (Z)-1-(piperidin-1-yl)octadec-9-en-1-one (4637-46-1)

Guidance literature:

With silica gel; at 130 ℃; for 1.33333h; Microwave irradiation; Green chemistry;

DOI:10.1039/c5gc00189g

Reference yield:

piperidine (110-89-4) + Methyl oleate (112-62-9) → (Z)-1-(piperidin-1-yl)octadec-9-en-1-one (4637-46-1)

Guidance literature:

In acetonitrile; for 24h;

DOI:10.1016/j.bmc.2014.11.019

upstream raw materials:

piperidine

(Z)-9-octadecenoyl chloride

cis-Octadecenoic acid

Methyl oleate

Refernces

• 1、 Ojeda-Porras, Andrea,Hernández-Santana, Alejandra,Gamba-Sánchez, Diego. "Direct amidation of carboxylic acids with amines under microwave irradiation using silica gel as a solid support". supporting information. p. 3157 - 3163. Retrieved 2015/05/27.