pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate

Base Information

Chemical Name:pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate
CAS No.:1359843-97-2
Molecular Formula:C₂₁H₂₅BO₄
Molecular Weight:352.238
Hs Code.:

Synonyms:

Suppliers and Price of pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate

There total 7 articles about pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1359844-58-8
2-phenyl-5-iodobenzylbromide

: 1359843-97-2
pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 0.5 h / -78 °C

1.2: 3 h / -78 °C

2.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 3 h / 80 °C

3.1: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine; trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; n-heptane; dichloromethane; ethylbenzene; 2.1: Suzuki coupling;
DOI:10.1016/j.bmcl.2011.12.043

Reference yield:

: 1359843-93-8
tert-butyl 3-(2-phenyl-5-iodophenyl)propanoate

: 1359843-97-2
pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 3 h / 80 °C

2: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine; trifluoroacetic acid; In 1,4-dioxane; dichloromethane; 1: Suzuki coupling;
DOI:10.1016/j.bmcl.2011.12.043

Reference yield:

: 7149-70-4
2-bromo-5-nitrotoluene

: 1359843-97-2
pinacol(4-phenyl-(3-(2-carboxyethyl))phenyl)boronate

Guidance literature:: Multi-step reaction with 7 steps

1.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / butan-1-ol / 100 °C

2.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h / 3750.38 Torr

3.1: hydrogenchloride; sodium nitrite / water / 1 h / 0 °C / Cooling with ice

3.2: 0 - 20 °C

4.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Reflux

5.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 0.5 h / -78 °C

5.2: 3 h / -78 °C

6.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 3 h / 80 °C

7.1: trifluoroacetic acid / dichloromethane / 0.5 h / 20 °C

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; hydrogenchloride; potassium phosphate; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); palladium 10% on activated carbon; hydrogen; palladium diacetate; triethylamine; trifluoroacetic acid; lithium diisopropyl amide; sodium nitrite; In tetrahydrofuran; 1,4-dioxane; tetrachloromethane; ethanol; n-heptane; dichloromethane; ethylbenzene; water; butan-1-ol; 1.1: Suzuki coupling / 6.1: Suzuki coupling;
DOI:10.1016/j.bmcl.2011.12.043