(-)-bostrycin

Base Information

• Chemical Name: (-)-bostrycin
• CAS No.: 122292-69-7
• Molecular Formula: C₁₆H₁₆O₈
• Molecular Weight: 336.298
• Mol file: 122292-69-7.mol

Synonyms:

Chemical Property of (-)-bostrycin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-bostrycin

There total 4 articles about (-)-bostrycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R,2S,3R)-5,6-O-diphenylmethylidene-1,2,3,4-tetrahydro-2,3-O-isopropylidene-3-methyl-9,10-dioxo-1-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyloxy)anthracene-2,3,5,6,8-pentaol (122204-19-7) → (+)-bostrycin (21879-81-2,97467-36-2,122292-69-7)

Guidance literature:

With hydrogenchloride; In ethanol; for 12h; Yield given; Heating;

DOI:10.1016/S0040-4020(01)85591-5

Reference yield:

(1R,2S,3R,4aR,9aR)-5,6-O-diphenylmethylidene-1,2,3,4,4a,9a-hexahydro-2,3-O-isopropylidene-3-methyl-9,10-dioxo-1-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyloxy)anthracene-2,3,5,6,8-pentaol (132335-80-9) → (+)-bostrycin (21879-81-2,97467-36-2,122292-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / activated manganese dioxide / benzene / 7 h / Heating

2: 1M HCl / ethanol / 12 h / Heating

With hydrogenchloride; manganese(IV) oxide; In ethanol; benzene;

DOI:10.1016/S0040-4020(01)85591-5

Reference yield:

C43H42O15 → (+)-bostrycin (21879-81-2,97467-36-2,122292-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acid

With acid;

DOI:10.1039/c39890000017

upstream raw materials:

diazomethane

(1R,2S,3R)-5,6-O-diphenylmethylidene-1,2,3,4-tetrahydro-2,3-O-isopropylidene-3-methyl-9,10-dioxo-1-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyloxy)anthracene-2,3,5,6,8-pentaol

(1R,2S,3R,4aR,9aR)-5,6-O-diphenylmethylidene-1,2,3,4,4a,9a-hexahydro-2,3-O-isopropylidene-3-methyl-9,10-dioxo-1-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyloxy)anthracene-2,3,5,6,8-pentaol

Downstream raw materials:

6-(4'-phenylpiperidin-1-yl)-6-demethoxybostrycin

6-(p-methoxyphenylamino)-6-demethoxybostrycin

6-(p-methoxybenzylamino)-6-demethoxybostrycin

6-(phenylamino)-6-demethoxybostrycin