Palmitoleic Acid-d14

Base Information

• Chemical Name: Palmitoleic Acid-d14
• CAS No.: 184708-66-5
• Molecular Formula: C₁₆H₃₀O₂
• Molecular Weight: 268.302
• Mol file: 184708-66-5.mol

Synonyms:

Chemical Property of Palmitoleic Acid-d14

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Palmitoleic Acid-d14 ≥99% deuterated forms (d1-d14) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: Palmitoleic acid-d14 contains 14 deuterium atoms at the 2, 2’, 3, 3’, 4, 4’, 5, 5’, 6, 6’, 7, 7’, 8, and 8’ positions. It is intended for use as an internal standard for the quantification of palmitoleic acid . Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. It is found mainly in animal fats, particularly in fish and marine mammals, and is also present in the seeds of plants of the Proteaceae family. In contrast to a diet enriched with oleic acid , palmitoleic acid-based diets raise low density lipoprotein (LDL) cholesterol and lower high density lipoprotein (HDL) cholesterol much like that of a saturated fatty acid, even when dietary intake of cholesterol is maintained at a low level.

Technology Process of Palmitoleic Acid-d14

There total 4 articles about Palmitoleic Acid-d14 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-octynyllithium (21433-45-4) → palmitoleic acid-2,2,3,3,4,4,5,5,6,6,7,7,8,8-d14 (184708-66-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / tetrahydrofuran; hexane / 8 h / Ambient temperature

2: 94 percent / p-TsOH / methanol / 4 h / Ambient temperature

3: 1.) hydrogen, Lindlar catalyst, 2.) PDC / 1.) ethanol, 2 h, 2.) DMF, room temperature, 24 h

With Lindlar's catalyst; dipyridinium dichromate; hydrogen; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; hexane;

DOI:10.1021/jo961423f

Reference yield:

tetrahydropyrany hexadecyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-d16 ether (184708-62-1) → palmitoleic acid-2,2,3,3,4,4,5,5,6,6,7,7,8,8-d14 (184708-66-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / tetrahydrofuran; hexane / 8 h / Ambient temperature

2: 94 percent / p-TsOH / methanol / 4 h / Ambient temperature

3: 1.) hydrogen, Lindlar catalyst, 2.) PDC / 1.) ethanol, 2 h, 2.) DMF, room temperature, 24 h

With Lindlar's catalyst; dipyridinium dichromate; hydrogen; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; hexane;

DOI:10.1021/jo961423f

Reference yield:

1-(tetrahydropyranyloxy)-9-hexadecyne-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-d16 (184708-64-3) → palmitoleic acid-2,2,3,3,4,4,5,5,6,6,7,7,8,8-d14 (184708-66-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / p-TsOH / methanol / 4 h / Ambient temperature

2: 1.) hydrogen, Lindlar catalyst, 2.) PDC / 1.) ethanol, 2 h, 2.) DMF, room temperature, 24 h

With Lindlar's catalyst; dipyridinium dichromate; hydrogen; toluene-4-sulfonic acid; In methanol;

DOI:10.1021/jo961423f

upstream raw materials:

9-hexadecyn-1-ol-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-d₁₆

1-octynyllithium

tetrahydropyrany hexadecyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-d₁₆ ether

1-(tetrahydropyranyloxy)-9-hexadecyne-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-d₁₆

Refernces