Technology Process of C25H21FN2O2
There total 3 articles about C25H21FN2O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hexamethyldisilazane / tetrahydrofuran / -78 - 0 °C
2: N,N-dimethyl-formamide / 12 h / 20 °C / Molecular sieve
3: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C
4: hydrazine hydrochloride / ethanol; water / 60 °C
5: water; sodium hydroxide / tetrahydrofuran; ethanol / 12 h / 50 °C
With
hydrazine hydrochloride; water; sodium hexamethyldisilazane; potassium carbonate; sodium hydroxide;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.05.020
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C
2: hydrazine hydrochloride / ethanol; water / 60 °C
3: water; sodium hydroxide / tetrahydrofuran; ethanol / 12 h / 50 °C
With
hydrazine hydrochloride; water; potassium carbonate; sodium hydroxide;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.05.020