(3R,4S,Z)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate

Base Information

Chemical Name:(3R,4S,Z)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate
CAS No.:1403324-74-2
Molecular Formula:C₃₀H₄₆N₂O₇
Molecular Weight:546.704
Hs Code.:

(3R,4S,Z)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate

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Chemical Property of (3R,4S,Z)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate

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Technology Process of (3R,4S,Z)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate

There total 1 articles about (3R,4S,Z)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₅H₁₉NO₄

: 2748-02-9,13081-32-8
L-leucine tert-butyl ester hydrochloride

: 1403324-74-2
(3R,4S,Z)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate

: 1403324-64-0
(3R,4S,E)-5-(((S)-1-(tert-butoxy)-4-methyl-1-oxopentan-2-yl)-amino)-4-((tert-butoxycarbonyl)amino)-2-ethylidene-3-methyl-5-oxopentyl benzoate

Guidance literature:: C₁₅H₁₉NO₄; With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In acetonitrile; at 20 ℃; for 0.05h; Inert atmosphere;

L-leucine tert-butyl ester hydrochloride; In acetonitrile; for 20h; Overall yield = 138 mg;
DOI:10.1021/jo301723y