alpha(4-(Trimethylsilyl)phenyl)benzhydrol

Base Information

• Chemical Name: alpha(4-(Trimethylsilyl)phenyl)benzhydrol
• CAS No.: 50653-05-9
• Molecular Formula: C₂₂H₂₄OSi
• Molecular Weight: 332.517
• European Community (EC) Number: 659-399-0
• Mol file: 50653-05-9.mol

Synonyms:Diphenyl(4-(trimethylsilyl)phenyl)methanol;50653-05-9;ALPHA(4-(TRIMETHYLSILYL)PHENYL)BENZHYDROL;AKOS024338463

Chemical Property of alpha(4-(Trimethylsilyl)phenyl)benzhydrol

Chemical Property:

• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 332.159641919
• Heavy Atom Count: 24
• Complexity: 361

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C[Si](C)(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O

Technology Process of alpha(4-(Trimethylsilyl)phenyl)benzhydrol

There total 2 articles about alpha(4-(Trimethylsilyl)phenyl)benzhydrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1.4-dibromobenzene (106-37-6) → <4-(trimethylsilyl)phenyl>diphenylcarbinol (50653-05-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Mg / 1.) ether, 2.) 24 h, reflux

2: 1.) Mg / 1.) ether, 2.) benzene, 12 h, reflux

With magnesium;

DOI:10.1021/jo00320a003

Reference yield:

→ <4-(trimethylsilyl)phenyl>diphenylcarbinol (50653-05-9)

Guidance literature:

Keton 12b, 4-Trimethylsilylphenyl-Li 9b;

DOI:10.1002/ardp.19783111105

Reference yield:

<4-(trimethylsilyl)phenyl>diphenylcarbinol (50653-05-9) → <4-(trimethylsilyl)phenyl>diphenylchloromethane (76446-92-9)

Guidance literature:

With acetyl chloride; In benzene;

DOI:10.1021/jo00320a003

upstream raw materials:

1.4-dibromobenzene

Downstream raw materials:

<4-(trimethylsilyl)phenyl>diphenylchloromethane

<4-(trimethylsilyl)phenyl>diphenylmethane

C₂₂H₂₃Si^(1-)