C₁₅H₈Cl₂FN

Base Information

• Chemical Name: C₁₅H₈Cl₂FN
• CAS No.: 1168136-18-2
• Molecular Formula: C₁₅H₈Cl₂FN
• Molecular Weight: 292.14
• Mol file: 1168136-18-2.mol

Synonyms:

Chemical Property of C₁₅H₈Cl₂FN

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₁₅H₈Cl₂FN

There total 1 articles about C₁₅H₈Cl₂FN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3‐dichloro‐4‐iodoisoquinoline (1168136-15-9) + 4-fluoroboronic acid (1765-93-1) → C15H8Cl2FN (1168136-18-2) + C21H12ClF2N (1168136-25-1)

Guidance literature:

1,3‐dichloro‐4‐iodoisoquinoline; 4-fluoroboronic acid; With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In 1,3-dioxane; water; at 55 ℃; for 12h;

at 55 ℃; for 12h;

DOI:10.1016/j.tetlet.2009.04.040

upstream raw materials:

1,3‐dichloro‐4‐iodoisoquinoline

4-fluoroboronic acid