{(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

Base Information

Chemical Name:{(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane
CAS No.:128322-25-8
Molecular Formula:C₄₃H₆₈O₆Si
Molecular Weight:709.095
Hs Code.:

{(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

Synonyms:

Suppliers and Price of {(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

There total 18 articles about {(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78508-96-0
(5S)-5-(hydroxymethyl)-5H-furan-2-one

: 128322-25-8
{(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 17 steps

1: 93 percent / dl-camphorsulfonic acid (CSA)

2: 1.) LDA / 1.) THF, -78 deg C

3: 1.) diisobutylaluminium hydride, 2.) sodium borohydride / 1.) THF, -78 deg C

4: imidazole

5: i-Pr₂NEt

6: lithium aluminium hydride

7: NaH

8: MgBr₂ / diethyl ether / 20 °C

9: COCl₂, Et₃N / dimethylsulfoxide

10: 85 percent / tetrahydrofuran / -78 °C

11: Hg(OAc)2 / 48 h / 135 °C

12: 76 percent / tetrahydrofuran / -78 °C

13: Hg(OAc)2 / 48 h / 135 °C

14: NaBH₄

15: Et₃N

16: sodium iodide / acetone

17: 1.) t-BuLi / 1.) THF, -78 deg C, then 0 deg C

With 1H-imidazole; sodium tetrahydroborate; lithium aluminium tetrahydride; camphor-10-sulfonic acid; mercury(II) diacetate; tert.-butyl lithium; sodium hydride; diisobutylaluminium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; sodium iodide; magnesium bromide; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; acetone;
DOI:10.1016/S0040-4039(01)93503-8

Reference yield:

: 81703-94-8
methyl (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate

: 128322-25-8
{(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 18 steps

1: 95 percent / dl-camphorsulfonic acid (CSA) / methanol / 20 °C

2: 93 percent / dl-camphorsulfonic acid (CSA)

3: 1.) LDA / 1.) THF, -78 deg C

4: 1.) diisobutylaluminium hydride, 2.) sodium borohydride / 1.) THF, -78 deg C

5: imidazole

6: i-Pr₂NEt

7: lithium aluminium hydride

8: NaH

9: MgBr₂ / diethyl ether / 20 °C

10: COCl₂, Et₃N / dimethylsulfoxide

11: 85 percent / tetrahydrofuran / -78 °C

12: Hg(OAc)2 / 48 h / 135 °C

13: 76 percent / tetrahydrofuran / -78 °C

14: Hg(OAc)2 / 48 h / 135 °C

15: NaBH₄

16: Et₃N

17: sodium iodide / acetone

18: 1.) t-BuLi / 1.) THF, -78 deg C, then 0 deg C

With 1H-imidazole; sodium tetrahydroborate; lithium aluminium tetrahydride; camphor-10-sulfonic acid; mercury(II) diacetate; tert.-butyl lithium; sodium hydride; diisobutylaluminium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; sodium iodide; magnesium bromide; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethyl ether; dimethyl sulfoxide; acetone;
DOI:10.1016/S0040-4039(01)93503-8

Reference yield:

: 128387-70-2
(4S)-4-hydroxy-5-tetrahydropyranyloxy-2-pentenoic acid γ-lactone

: 128322-25-8
{(5E,9E)-(3S,4S)-4-Benzyloxymethoxy-14-ethoxy-3-[2-(4-methoxy-benzyloxy)-ethyl]-6,10-dimethyl-pentadeca-5,9,14-trienyloxy}-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 16 steps

1: 1.) LDA / 1.) THF, -78 deg C

2: 1.) diisobutylaluminium hydride, 2.) sodium borohydride / 1.) THF, -78 deg C

3: imidazole

4: i-Pr₂NEt

5: lithium aluminium hydride

6: NaH

7: MgBr₂ / diethyl ether / 20 °C

8: COCl₂, Et₃N / dimethylsulfoxide

9: 85 percent / tetrahydrofuran / -78 °C

10: Hg(OAc)2 / 48 h / 135 °C

11: 76 percent / tetrahydrofuran / -78 °C

12: Hg(OAc)2 / 48 h / 135 °C

13: NaBH₄

14: Et₃N

15: sodium iodide / acetone

16: 1.) t-BuLi / 1.) THF, -78 deg C, then 0 deg C

With 1H-imidazole; sodium tetrahydroborate; lithium aluminium tetrahydride; mercury(II) diacetate; tert.-butyl lithium; sodium hydride; diisobutylaluminium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; sodium iodide; magnesium bromide; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; acetone;
DOI:10.1016/S0040-4039(01)93503-8