4-(Furan-2-yl)phenyl(phenyl)methanone

Base Information

• Chemical Name: 4-(Furan-2-yl)phenyl(phenyl)methanone
• CAS No.: 128373-20-6
• Molecular Formula: C17H12O2
• Molecular Weight: 248.27600
• DSSTox Substance ID: DTXSID601291943
• Nikkaji Number: J2.516.893C
• Mol file: 128373-20-6.mol

Synonyms:128373-20-6;[4-(furan-2-yl)phenyl]-phenylmethanone;[4-(Furan-2-yl)phenyl](phenyl)methanone;4-(Furan-2-yl)phenyl(phenyl)methanone;DTXSID601291943;[4-(2-Furanyl)phenyl]phenylmethanone

Chemical Property of 4-(Furan-2-yl)phenyl(phenyl)methanone

Chemical Property:

• Melting Point: 80-82℃
• PSA: 30.21000
• LogP: 4.17760
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 248.083729621
• Heavy Atom Count: 19
• Complexity: 298

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C3=CC=CO3

Technology Process of 4-(Furan-2-yl)phenyl(phenyl)methanone

There total 4 articles about 4-(Furan-2-yl)phenyl(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-furylzinc chloride (81745-86-0) + 4-chlorobenzophenone (134-85-0) → (4-(furan-2-yl)phenyl)(phenyl)methanone (128373-20-6)

Guidance literature:

With C₂₇H₂₂Cl₂N₃NiP; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; for 1.5h; Inert atmosphere; Schlenk technique; Heating;

DOI:10.1039/c2dt30886j

Reference yield: 99.0%

p-PhC(O)C6H4NMe3(+)*I(-) (31688-74-1) + 2-furylzinc chloride (81745-86-0) → (4-(furan-2-yl)phenyl)(phenyl)methanone (128373-20-6)

Guidance literature:

With C₃₂H₂₆ClN₂NiP; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; at 85 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jo300209d

Reference yield: 99.0%

furan (110-00-9) + 4-chlorobenzophenone (134-85-0) → (4-(furan-2-yl)phenyl)(phenyl)methanone (128373-20-6)

Guidance literature:

furan; With n-butyllithium; In diethyl ether;

With zinc(II) chloride;

4-chlorobenzophenone; nickel amido phosphine pincer complex; In tetrahydrofuran; diethyl ether; at 70 ℃; for 10h; Further stages.;

DOI:10.1021/ol701927g

upstream raw materials:

furan

4-chlorobenzophenone

p-PhC(O)C₆H₄NMe₃(+)*I(-)

2-furylzinc chloride