Technology Process of C27H22BrN7O6S
There total 4 articles about C27H22BrN7O6S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C23H21N5O6S;
With
sodium hydride;
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
at 20 ℃;
for 0.0833333h;
5-Bromo-2-chloropyrimidine;
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
at 70 ℃;
for 29h;
DOI:10.1021/jm3009103
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium tert-butylate / methanol
2.1: N,N-dimethyl-formamide / 16 h / 20 °C
3.1: potassium tert-butylate / 1,2-dimethoxyethane / 17 h / 20 - 90 °C
4.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide; mineral oil / 0.08 h / 20 °C
4.2: 29 h / 70 °C
With
potassium tert-butylate; sodium hydride;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/jm3009103
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N,N-dimethyl-formamide / 16 h / 20 °C
2.1: potassium tert-butylate / 1,2-dimethoxyethane / 17 h / 20 - 90 °C
3.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide; mineral oil / 0.08 h / 20 °C
3.2: 29 h / 70 °C
With
potassium tert-butylate; sodium hydride;
In
tetrahydrofuran; 1,2-dimethoxyethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/jm3009103
