N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide

Base Information

• Chemical Name: N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide
• CAS No.: 1449608-01-8
• Molecular Formula: C₂₄H₂₂BrNO
• Molecular Weight: 420.349
• Mol file: 1449608-01-8.mol

Synonyms:

Chemical Property of N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide

There total 2 articles about N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H14BrN (1012050-86-0) → N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide (1449608-01-8)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) chloride / acetonitrile / 0.5 h / 20 °C / Inert atmosphere

2: dichloromethane / 6 h / 45 °C / Inert atmosphere

With copper(l) chloride; In dichloromethane; acetonitrile;

DOI:10.1021/jo400974k

Reference yield:

C22H20BrNO + tri-n-butyl(vinyl)tin (7486-35-3) → N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide (1449608-01-8)

Guidance literature:

In dichloromethane; at 45 ℃; for 6h; Inert atmosphere;

DOI:10.1021/jo400974k

Reference yield:

N-benzyl-N-(1-(1-bromonaphthalen-2-yl)allyl)methacrylamide (1449608-01-8) → 12-benzyl-4-methyl-2-methylene-1,2,3,4-tetrahydro-1,4-(epiminomethano)phenanthren-11-one + 12-benzyl-2,4-dimethyl-1,4-dihydro-1,4-(epiminomethano)phenanthren-11-one

Guidance literature:

With tetrabutyl-ammonium chloride; palladium diacetate; sodium carbonate; In N,N-dimethyl-formamide; at 80 ℃; Overall yield = 65 %; Overall yield = 123 mg; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/jo400974k

upstream raw materials:

tri-n-butyl(vinyl)tin

C₁₈H₁₄BrN