3-((2S,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate

Base Information

• Chemical Name: 3-((2S,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate
• CAS No.: 1208000-88-7
• Molecular Formula: C₄₄H₄₄N₄O₉
• Molecular Weight: 772.855
• Mol file: 1208000-88-7.mol

Synonyms:

Chemical Property of 3-((2S,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-((2S,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate

There total 1 articles about 3-((2S,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-((3aR,4R,6R,6aR)-4-(hydroxymethyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate (1208000-86-5) + 4,4'-dimethoxytrityl chloride (40615-36-9) → 3-((2S,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate (1208000-88-7) + 3-((2R,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate (1208000-87-6)

Guidance literature:

With pyridine; for 3h; Inert atmosphere;

DOI:10.3390/molecules14114326

Reference yield:

3-((2S,3aR,4R,6R,6aR)-4-((bis(4-methoxyphenyl)(phenyl)methoxy)-methyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate (1208000-88-7) → 3-((2S,3aR,4R,6R,6aR)-6-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(3-hydroxypropyl)-2-methyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purin-6(9H)-one

Guidance literature:

With ammonia; water; In methanol; at 20 ℃; for 72h;

DOI:10.3390/molecules14114326

upstream raw materials:

3-((3aR,4R,6R,6aR)-4-(hydroxymethyl)-2-methyl-6-(6-oxo-1,6-dihydropurin-9-yl)-tetrahydrofuro[3,4-d][1,3]dioxol-2-yl)propyl 4-methylbenzoate

4,4'-dimethoxytrityl chloride