(R)-4-BENZYL-2-OXAZOLIDINONE LITHIUM SALT

Base Information

• Chemical Name: (R)-4-BENZYL-2-OXAZOLIDINONE LITHIUM SALT
• CAS No.: 128677-61-2
• Molecular Formula: C₁₀H₁₀NO₂*Li
• Molecular Weight: 183.136
• Mol file: 128677-61-2.mol

Synonyms:lithium (4S)-4-benzyl-1,3-oxazolidin-2-one;(S)-4-Benzyl-2-oxazolidinone lithium azaenolate;(S)-4-benzyl-2-oxazolidinone lithium salt;4(RS)-trimethylsiloxy-4-methyl-1-octyne;[[1-methyl-1-[2-propynyl]pentyl]oxy]trimethylsilane;4(RS)-4-trimethylsilyloxy-4-methyl-1-octyne;4(S)-(phenylmethyl)-2-oxazolidinone lithium salt;Silane,trimethyl[[1-methyl-1-(2-propynyl)pentyl]oxy];4-methyl-4-trimethylsiloxy-1octyne;lithium salt of (S)-4-benzyl-2-oxazolidinone;(4S)-4-(phenylmethyl)-2-oxazolidinone lithium salt;(S)-4-<(3,4-Dimethoxybenzyloxy)methyl>-2,2-dimethyl-1,3-dioxolane;<(1-butyl-1-methyl-3-butynyl)oxy>trimethylsilane;4-(S)-(((3,4-dimethoxybenzyl)oxy)methyl)-2,2-dimethyl-1,3-dioxolane;4-methyl-4-trimethylsilyloxy-1-octyne;4-methyl-1-octyn-4-ol trimethylsilyl ether;

Chemical Property of (R)-4-BENZYL-2-OXAZOLIDINONE LITHIUM SALT

Chemical Property:

• PSA: 29.54000
• LogP: 1.45210

Purity/Quality:

(R)-4-BENZYL-2-OXAZOLIDINONE LITHIUM SALT 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-4-BENZYL-2-OXAZOLIDINONE LITHIUM SALT

There total 1 articles about (R)-4-BENZYL-2-OXAZOLIDINONE LITHIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-4-Benzyl-2-oxazolidinone (90719-32-7) → (S)-4-benzyl-2-oxazolidinone lithium salt (101711-90-4,123731-35-1,128677-61-2)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -35 - 0 ℃;

Reference yield: 100.0%

(3S,4R)-4-(4-benzyloxy-3-methoxyphenyl)-3-methyl-4-(triisopropylsilyloxy)butanoic acid + (S)-4-benzyl-2-oxazolidinone lithium salt (101711-90-4,123731-35-1,128677-61-2) → (S)-4-benzyl-3-[(3S,4R)-4-(4-benzyloxy-3-methoxyphenyl)-3-methyl-4-(triisopropylsilyloxy)butanoyl]-2-oxazolidinone

Guidance literature:

(3S,4R)-4-(4-benzyloxy-3-methoxyphenyl)-3-methyl-4-(triisopropylsilyloxy)butanoic acid; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at -75 - 0 ℃; for 1h;

(S)-4-benzyl-2-oxazolidinone lithium salt; In tetrahydrofuran; at -75 - 0 ℃; for 1h;

DOI:10.1080/09168451.2014.877833

Reference yield: 96.0%

C29H46O4Si2 + (S)-4-benzyl-2-oxazolidinone lithium salt (101711-90-4,123731-35-1,128677-61-2) → (S)-4-benzyl-3-((4S,5S)-5-((tert-butyldimethylsilyl)oxy)-6-((tert-butyldiphenylsilyl)oxy)-4-methylhexanoyl)oxazolidin-2-one

Guidance literature:

C₂₉H₄₆O₄Si₂; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at -78 - 0 ℃; for 0.5h; Inert atmosphere;

(S)-4-benzyl-2-oxazolidinone lithium salt; In tetrahydrofuran; at -78 ℃; for 0.666667h; Inert atmosphere;

upstream raw materials:

(S)-4-Benzyl-2-oxazolidinone

Downstream raw materials:

<4S>-3-<2--N-Methylamino>-1-oxoethyl>-4-(phenylmethyl)-2-oxazolidinone

3-<4-(1,3-dioxolan-2-yl)-1-oxo-3(S)-phenylbutyl>-4(S)-(phenylmethyl)-2-oxazolidinone

3-<4-(1,3-dioxolan-2-yl)-1-oxo-3(R)-phenylbutyl>-4(S)-(phenylmethyl)-2-oxazolidinone

(4S)-3-((E,E)-2',7',9'-decatrienoyl)-4-(phenylmethyl)-2-oxazolidinone

Refernces

• 1、 Yamauchi, Satoshi,Tomiyama, Chisato,Wukirsari, Tuti,Nishiwaki, Hisashi. "Syntheses of all the stereoisomers of butanol type 1,7-seco-2,7′-cyclolignane". . p. 19 - 28. Retrieved 2015/07/27.
• 2、 -. "N-FORMYL HYDROZYAMINE COMPOUNDS". Page/Page column 7-8. . Retrieved 2009/04/24.