diethylaminochloro-2-methylphenylphosphine

Base Information

• Chemical Name: diethylaminochloro-2-methylphenylphosphine
• CAS No.: 90928-96-4
• Molecular Formula: C₁₁H₁₇ClNP
• Molecular Weight: 229.689
• Mol file: 90928-96-4.mol

Synonyms:

Chemical Property of diethylaminochloro-2-methylphenylphosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethylaminochloro-2-methylphenylphosphine

There total 1 articles about diethylaminochloro-2-methylphenylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylphenyl bromide (95-46-5) → diethylaminochloro-2-methylphenylphosphine (90928-96-4)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/S0040-4020(01)91106-8

Reference yield:

1-bromo-2-bis(2-methylphenyl)phosphinobenzene (924908-01-0) + diethylaminochloro-2-methylphenylphosphine (90928-96-4) → C31H35NP2

Guidance literature:

1-bromo-2-bis(2-methylphenyl)phosphinobenzene; With n-butyllithium; In diethyl ether; hexane; at -70 ℃; Inert atmosphere; Schlenk technique;

diethylaminochloro-2-methylphenylphosphine; In diethyl ether; hexane; at 0 - 20 ℃; for 16h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.chemmater.0c02683

Reference yield:

diethylaminochloro-2-methylphenylphosphine (90928-96-4) → chloro(diphenylmethyl)-2-methylphenyl phosphine (90929-00-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 1.5N n-butyllithium / 1.) THF, hexane, 2.) 20h, RT

2: 90 percent / HCl / tetrahydrofuran / 1 h / Ambient temperature

With hydrogenchloride; n-butyllithium; In tetrahydrofuran;

DOI:10.1016/S0040-4020(01)91106-8

upstream raw materials:

2-methylphenyl bromide

Downstream raw materials:

diethylamino(diphenylmethyl)-2-methylphenylphosphine

chloro(diphenylmethyl)-2-methylphenyl phosphine