2-(9h-Purin-9-yl)cyclopentanol

Base Information

Chemical Name:2-(9h-Purin-9-yl)cyclopentanol
CAS No.:7400-58-0
Molecular Formula:C₁₀H₁₂N₄O
Molecular Weight:204.231
Hs Code.:
NSC Number:35003
DSSTox Substance ID:DTXSID50284035

Synonyms:2-(9h-purin-9-yl)cyclopentanol;DTXSID50284035;NSC35003;NSC-35003

Suppliers and Price of 2-(9h-Purin-9-yl)cyclopentanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(9h-Purin-9-yl)cyclopentanol

Chemical Property:

Vapor Pressure:5.94E-08mmHg at 25°C
Boiling Point:424.2°C at 760 mmHg
Flash Point:210.3°C
Density:1.56g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:204.10111102
Heavy Atom Count:15
Complexity:238

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C(C1)O)N2C=NC3=CN=CN=C32

Technology Process of 2-(9h-Purin-9-yl)cyclopentanol

There total 4 articles about 2-(9h-Purin-9-yl)cyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(9H-Purin-9-yl)cyclopentan-1-one

: (1R,2S)-2-(9H-Purin-9-yl)cyclopentan-1-ol

: 7400-58-0,99069-48-4
2-(9H-Purin-9-yl)cyclopentan-1-ol

Guidance literature:: With formic acid; [(R,R)-N-(2-amino-1,2-diphenylethyl)pentafluorobenzenesulfonamide]chloride(p-cymene)ruthenium (II); triethylamine; In 1,4-dioxane; at 27 ℃; for 24h; Overall yield = 91 %; Overall yield = 18.6 mg; stereoselective reaction;
DOI:10.1021/acs.orglett.9b00451

Reference yield:

: 694-28-0
2-chlorocyclopentanone

: 120-73-0
purine

: (1R,2S)-2-(9H-Purin-9-yl)cyclopentan-1-ol

: 7400-58-0,99069-48-4
2-(9H-Purin-9-yl)cyclopentan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 24 h / 50 °C

2: triethylamine; [(R,R)-N-(2-amino-1,2-diphenylethyl)pentafluorobenzenesulfonamide]chloride(p-cymene)ruthenium (II); formic acid / 1,4-dioxane / 24 h / 27 °C

With formic acid; [(R,R)-N-(2-amino-1,2-diphenylethyl)pentafluorobenzenesulfonamide]chloride(p-cymene)ruthenium (II); potassium carbonate; triethylamine; In 1,4-dioxane; acetonitrile;
DOI:10.1021/acs.orglett.9b00451