Phthalamidsaeureethylester

Base Information

• Chemical Name: Phthalamidsaeureethylester
• CAS No.: 100905-46-2
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.202
• Mol file: 100905-46-2.mol

Synonyms:

Chemical Property of Phthalamidsaeureethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phthalamidsaeureethylester

There total 3 articles about Phthalamidsaeureethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

2-cyano-benzoic acid ethyl ester (6525-45-7) → phthalimide (136918-14-4,85-41-6) + Phthalamidsaeureethylester (100905-46-2)

Guidance literature:

With indium(III) chloride; Acetaldehyde oxime; In toluene; for 6h; Reflux;

DOI:10.1016/j.tetlet.2010.01.063

Reference yield:

monoethyl phthalate (2306-33-4) → Phthalamidsaeureethylester (100905-46-2)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride, DMF / CH₂Cl₂

2: 1.) hexamethyldisilazane, 2.) 5percent aq. H₂SO₄ / 1.) CH₂Cl₂, room temp., 2.) CH₃OH

With oxalyl dichloride; sulfuric acid; N,N-dimethyl-formamide; 1,1,1,3,3,3-hexamethyl-disilazane; In dichloromethane;

DOI:10.1055/s-1985-31257

Reference yield:

→ Phthalamidsaeureethylester (100905-46-2)

Guidance literature:

Phthalimid-Ag-salz, EtI;

DOI:10.1248/cpb.22.2999

upstream raw materials:

monoethyl phthalate

2-cyano-benzoic acid ethyl ester

Refernces

• 1、 Matoba,Yamazaki. "Reduction of O alkylated imides". . p. 2999 - 3001. Retrieved 1974.