Cyclopentanon-3,4-trans-dicarbonsaeure

Base Information

• Chemical Name: Cyclopentanon-3,4-trans-dicarbonsaeure
• CAS No.: 3128-17-4
• Molecular Formula: C₇H₈O₅
• Molecular Weight: 172.138
• Mol file: 3128-17-4.mol

Synonyms:

Chemical Property of Cyclopentanon-3,4-trans-dicarbonsaeure

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopentanon-3,4-trans-dicarbonsaeure

There total 12 articles about Cyclopentanon-3,4-trans-dicarbonsaeure which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1,2,3,4-butanetetracarboxylic acid tetraethyl ester (4373-15-3) → racemic trans-cyclopentanone-3,4-dicarboxylic acid (1703-61-3,3128-17-4,3128-18-5,67885-97-6)

Guidance literature:

1,2,3,4-butanetetracarboxylic acid tetraethyl ester; With sodium methylate; In methanol; at 20 - 22 ℃; for 16h;

With hydrogenchloride; methanol; water; at 100 ℃; for 16.25h; Heating / reflux;

Reference yield: 64.0%

(1R,2R)-4-oxo-1,2-cyclopentanedicarboxylic acid bis-(1R,2S)-(-)-ephedrine salt → ephedrine (299-42-3,7009-81-6,90-83-5,6912-63-6) + (1R,2R)-4-oxocyclopentane-1,2-dicarboxylic acid (1703-61-3,3128-17-4,3128-18-5,67885-97-6)

Guidance literature:

(1R,2R)-4-oxo-1,2-cyclopentanedicarboxylic acid bis-(1R,2S)-(-)-ephedrine salt; With potassium hydroxide; In water; for 0.0833333h;

With hydrogenchloride; In water;

Reference yield: 60.4%

(+)-(1S,2S)-dimethyl-4-oxocyclopentane 1,2-dicarboxylate (115794-30-4) → (1R,2R)-4-oxocyclopentane-1,2-dicarboxylic acid (1703-61-3,3128-17-4,3128-18-5,67885-97-6)

Guidance literature:

With hydrogenchloride; water; In 1,4-dioxane; at 100 ℃; for 16h;

upstream raw materials:

1,2,3,4-butanetetracarboxylic acid

1,2,3,4-butanetetracarboxylic acid tetraethyl ester

(+)-(1S,2S)-dimethyl-4-oxocyclopentane 1,2-dicarboxylate

trans(3,4)-3-Hydroxymethyl-4-(1',2'-dihydroxy-ethyl)-cyclopentanol-⁽¹⁾

Downstream raw materials:

(1R,4R,5R)-3-oxo-2-oxabicyclo[2.2.1]heptane-5-carboxylic acid

methyl (1R,2R,4S)-2-[5-hexen-1-yl(methyl)carbamoyl]-4-[[2-(4-isopropyl-1,3-thiazol-2-yl)-7-methoxy-8-methyl-4-quinolinyl]oxy]cyclopentanecarboxylate

(1R,2R,4S)-1-benzyl 2-methyl 4-hydroxycyclopentane-1,2-dicarboxylate

benzyl methyl (1R,2R,4R)-4-hydroxy-1,2-cyclopentanedicarboxylate