C₂₇H₂₉N₅O₃

Base Information

• Chemical Name: C₂₇H₂₉N₅O₃
• CAS No.: 1401318-34-0
• Molecular Formula: C₂₇H₂₉N₅O₃
• Molecular Weight: 471.559
• Mol file: 1401318-34-0.mol

Synonyms:

Chemical Property of C₂₇H₂₉N₅O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₂₉N₅O₃

There total 6 articles about C₂₇H₂₉N₅O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C14H21N5O2 + biphenyl-4-carboxylic acid (92-92-2) → C27H29N5O3 (1401318-34-0)

Guidance literature:

In dichloromethane; Inert atmosphere;

DOI:10.5012/bkcs.2012.33.8.2762

Reference yield:

Z-Lys(Boc)-OH (2389-60-8) → C27H29N5O3 (1401318-34-0)

Guidance literature:

Multi-step reaction with 6 steps

1: dicyclohexyl-carbodiimide; dmap / Inert atmosphere

2: lithium borohydride / tetrahydrofuran / Inert atmosphere

3: methanesulfonyl chloride / toluene / Inert atmosphere

4: tetrabutylammomium bromide; sodium azide / Inert atmosphere

5: trifluoroacetic acid / Inert atmosphere

6: dichloromethane / Inert atmosphere

With dmap; lithium borohydride; sodium azide; tetrabutylammomium bromide; methanesulfonyl chloride; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.5012/bkcs.2012.33.8.2762

Reference yield:

Nα-(benzyloxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine methyl ester (2389-49-3) → C27H29N5O3 (1401318-34-0)

Guidance literature:

Multi-step reaction with 5 steps

1: lithium borohydride / tetrahydrofuran / Inert atmosphere

2: methanesulfonyl chloride / toluene / Inert atmosphere

3: tetrabutylammomium bromide; sodium azide / Inert atmosphere

4: trifluoroacetic acid / Inert atmosphere

5: dichloromethane / Inert atmosphere

With lithium borohydride; sodium azide; tetrabutylammomium bromide; methanesulfonyl chloride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.5012/bkcs.2012.33.8.2762

upstream raw materials:

Z-Lys(Boc)-OH

biphenyl-4-carboxylic acid

N^α-(benzyloxycarbonyl)-N^ε-(tert-butoxycarbonyl)-L-lysine methyl ester

tert-butyl-N-[(5S)-5-(benzyloxycarbonylamino)-6-hydroxyhexyl]carbamate