anti-2-methylcyclopentylamine hydrochloride

Base Information

• Chemical Name: anti-2-methylcyclopentylamine hydrochloride
• CAS No.: 102778-37-0
• Molecular Formula: C₆H₁₃N*ClH
• Molecular Weight: 135.637
• Mol file: 102778-37-0.mol

Synonyms:

Chemical Property of anti-2-methylcyclopentylamine hydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of anti-2-methylcyclopentylamine hydrochloride

There total 5 articles about anti-2-methylcyclopentylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

→ anti-2-methylcyclopentylamine hydrochloride (5454-76-2,102778-36-9,102778-37-0,104485-20-3,115151-94-5)

Guidance literature:

Reference yield:

t-butyl (+/-)-(1S,4R)-2-oxa-3-azabicyclo[2.2.1]hept-5-ene-3-carboxylate → anti-2-methylcyclopentylamine hydrochloride (5454-76-2,102778-36-9,102778-37-0,104485-20-3,115151-94-5)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(II) chloride / tetrahydrofuran

2: TiCl₃

3: H₂ / Pd/C

4: HCl / diethyl ether

With hydrogenchloride; titanium(III) chloride; hydrogen; copper dichloride; palladium on activated charcoal; In tetrahydrofuran; diethyl ether;

DOI:10.1021/jo016275u

Reference yield:

((1R,2R)-2-Methyl-cyclopent-3-enyl)-carbamic acid tert-butyl ester → anti-2-methylcyclopentylamine hydrochloride (5454-76-2,102778-36-9,102778-37-0,104485-20-3,115151-94-5)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C

2: HCl / diethyl ether

With hydrogenchloride; hydrogen; palladium on activated charcoal; In diethyl ether;

DOI:10.1021/jo016275u