N-(2-azidobenzyl)cyclopropanamine

Base Information

• Chemical Name: N-(2-azidobenzyl)cyclopropanamine
• CAS No.: 1346523-81-6
• Molecular Formula: C₁₀H₁₂N₄
• Molecular Weight: 188.232
• Mol file: 1346523-81-6.mol

Synonyms:

Chemical Property of N-(2-azidobenzyl)cyclopropanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-(2-azidobenzyl)cyclopropanamine

There total 2 articles about N-(2-azidobenzyl)cyclopropanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H10N4 → N-(2-azidobenzyl)cyclopropanamine (1346523-81-6)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; at 0 - 20 ℃;

DOI:10.1021/jo2015054

Reference yield:

2-azidobenzaldehyde (16714-25-3) → N-(2-azidobenzyl)cyclopropanamine (1346523-81-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium sulfate / dichloromethane / 3 h / 20 °C

2: sodium cyanoborohydride; acetic acid / methanol / 0 - 20 °C

With sodium cyanoborohydride; acetic acid; sodium sulfate; In methanol; dichloromethane;

DOI:10.1021/jo2015054

Reference yield:

N-(2-azidobenzyl)cyclopropanamine (1346523-81-6) → C24H39N3O2

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 2 h / 20 °C / Molecular sieve

2: water; trimethylphosphane / tetrahydrofuran; toluene / 0 - 20 °C

With water; trimethylphosphane; In tetrahydrofuran; dichloromethane; toluene; 2: Staudinger reaction;

DOI:10.1021/jo2015054

upstream raw materials:

2-azidobenzaldehyde