caffeic acid

Base Information

• Chemical Name: caffeic acid
• CAS No.: 142039-77-8
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.177
• Mol file: 142039-77-8.mol

Synonyms:

Chemical Property of caffeic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of caffeic acid

There total 3 articles about caffeic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-allylpyrocatechol (1126-61-0) → caffeic acid (142039-77-8) + 4-(1-propenyl)-catechol

Guidance literature:

With rhodium complex ⁽⁵⁾; In chloroform; at 25 ℃; Product distribution; other rhodium catalyst;

DOI:10.1021/ja00153a012

Reference yield:

2-Methoxymethoxy-4-((E)-propenyl)-phenol (145134-25-4) → caffeic acid (142039-77-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / 210 - 220 °C

2: diethyl ether / Einleiten von NH₃

With diethyl ether; sodium acetate;

Reference yield:

4-allylpyrocatechol (1126-61-0) → caffeic acid (142039-77-8)

Guidance literature:

>; In chloroform; for 2h; other substrate, other catalyst, also with H₂;

upstream raw materials:

4-allylpyrocatechol

2-Methoxymethoxy-4-((E)-propenyl)-phenol

Downstream raw materials:

1,2-diethoxy-4-trans-propenyl-benzene