(E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

Base Information

Chemical Name:(E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one
CAS No.:102795-13-1
Molecular Formula:C₄₂H₆₂O₁₀S
Molecular Weight:759.014
Hs Code.:

(E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

Synonyms:

Suppliers and Price of (E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

There total 23 articles about (E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 102795-18-6
(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-9-methyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-yn-4-ol

: 102795-13-1
(E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

Guidance literature:: In diethyl ether;
DOI:10.1016/S0040-4039(00)98903-2

Reference yield:

: Trimethyl-[(Z)-2-((R)-2-phenyl-[1,3]dioxan-4-yl)-1-phenylsulfanyl-vinyl]-silane

: 102795-13-1
(E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

Guidance literature:: Multi-step reaction with 13 steps

1: 2.) KF / 1.) THF, hexane, 0 deg C_. Var: THF, -78 deg C

2: hydrogen / Pd/C

4: PPh₃, diethyl diazodicarboxylate / tetrahydrofuran / 5 °C

5: NaOMe / methanol

6: H⁽¹⁺⁾

7: n-Bu₄N⁽¹⁺⁾*F^(1-)

8: 1.) DMSO, (COCl)2, 2.) Et₃N

9: 83 percent

10: 1.) n-BuLi, 2.) H⁽¹⁺⁾

12: 1.)n-BuLi / 2.) THF

13: 98 percent / diethyl ether

With potassium fluoride; n-butyllithium; oxalyl dichloride; tetrabutyl ammonium fluoride; hydrogen; sodium methylate; hydrogen cation; dimethyl sulfoxide; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether;
DOI:10.1016/S0040-4039(00)98903-2

Reference yield:

: 102794-94-5
(R)-4-((S)-2-Benzenesulfonyl-1-methyl-ethyl)-2-phenyl-[1,3]dioxane

: 102795-13-1
(E)-(3R,8S,9S)-10-Benzenesulfonyl-3-benzyloxy-8-(1-ethoxy-ethoxy)-6,9-dimethyl-1-[(4S,6R)-2,2,6-trimethyl-6-(tetrahydro-pyran-2-yloxymethyl)-[1,3]dioxan-4-yl]-dec-5-en-4-one

Guidance literature:: Multi-step reaction with 12 steps

1: hydrogen / Pd/C

3: PPh₃, diethyl diazodicarboxylate / tetrahydrofuran / 5 °C

4: NaOMe / methanol

5: H⁽¹⁺⁾

6: n-Bu₄N⁽¹⁺⁾*F^(1-)

7: 1.) DMSO, (COCl)2, 2.) Et₃N

8: 83 percent

9: 1.) n-BuLi, 2.) H⁽¹⁺⁾

11: 1.)n-BuLi / 2.) THF

12: 98 percent / diethyl ether

With n-butyllithium; oxalyl dichloride; tetrabutyl ammonium fluoride; hydrogen; sodium methylate; hydrogen cation; dimethyl sulfoxide; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether;
DOI:10.1016/S0040-4039(00)98903-2