9,12,15-Octadecatrienoic acid, (2R)-2,3-dihydroxypropyl ester, (9Z,12Z,15Z)-

Base Information

• Chemical Name: 9,12,15-Octadecatrienoic acid, (2R)-2,3-dihydroxypropyl ester, (9Z,12Z,15Z)-
• CAS No.: 129828-42-8
• Molecular Formula: C21H36O4
• Mol file: 129828-42-8.mol

Synonyms:

Chemical Property of 9,12,15-Octadecatrienoic acid, (2R)-2,3-dihydroxypropyl ester, (9Z,12Z,15Z)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9,12,15-Octadecatrienoic acid, (2R)-2,3-dihydroxypropyl ester, (9Z,12Z,15Z)-

There total 2 articles about 9,12,15-Octadecatrienoic acid, (2R)-2,3-dihydroxypropyl ester, (9Z,12Z,15Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C24H40O4 → 1-linolenoyl-sn-glycerol (129828-42-8,56554-41-7,75685-85-7)

Guidance literature:

With Dowex; In methanol; at 20 ℃; for 15h;

DOI:10.1021/acs.jnatprod.6b00746

Reference yield:

(9Z,12Z,15Z)-octadeca-9-12,15-trienoic acid (463-40-1,1955-33-5,21661-10-9,21661-09-6,21661-13-2,21661-11-0) → 1-linolenoyl-sn-glycerol (129828-42-8,56554-41-7,75685-85-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 15 h / 20 °C

2: Dowex / methanol / 15 h / 20 °C

With dmap; dicyclohexyl-carbodiimide; In methanol; dichloromethane;

DOI:10.1021/acs.jnatprod.6b00746

Reference yield:

1-linolenoyl-sn-glycerol (129828-42-8,56554-41-7,75685-85-7) + (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride (39637-99-5,20445-33-4) → C31H43F3O6

Guidance literature:

With pyridine; at 20 ℃; for 16h;

DOI:10.1021/acs.jnatprod.6b00746

upstream raw materials:

(9Z,12Z,15Z)-octadeca-9-12,15-trienoic acid