2-Amino-4-bromo-3-methylbenzoic acid

Base Information

Chemical Name:2-Amino-4-bromo-3-methylbenzoic acid
CAS No.:129833-29-0
Molecular Formula:C8H8BrNO2
Molecular Weight:230.061
Hs Code.:
DSSTox Substance ID:DTXSID80564998
Wikidata:Q82449911

Synonyms:2-Amino-4-bromo-3-methylbenzoic acid;129833-29-0;Benzoic acid, 2-amino-4-bromo-3-methyl-;MFCD17244230;SCHEMBL2473014;DTXSID80564998;HTSCYFVXSZXFFV-UHFFFAOYSA-N;2-Amino-4-bromo-3-methylbenzoicacid;AC8749;AKOS008154362;2-amino-4-bromo-3-methyl-benzoic acid;AS-63956;SY195896;CS-0132956;EN300-93107;Z1037345876

Suppliers and Price of 2-Amino-4-bromo-3-methylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 2-Amino-4-bromo-3-methylbenzoic acid

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:228.97384
Heavy Atom Count:12
Complexity:186

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1N)C(=O)O)Br

Technology Process of 2-Amino-4-bromo-3-methylbenzoic acid

There total 4 articles about 2-Amino-4-bromo-3-methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 129833-54-1
6-bromo-7-methyl-1H-indole-2,3-dione

: 129833-29-0
2-amino-4-bromo-3-methylbenzoic acid

Guidance literature:: With water; dihydrogen peroxide; sodium hydroxide; at 20 ℃; for 1h;

Reference yield:

: 55289-36-6
3-bromo-2-methylaniline

: 129833-29-0
2-amino-4-bromo-3-methylbenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: Na₂SO₄, hydroxylamine sulfate, concd. HCl / H₂O

2: CH₃SO₃H / 70 - 80 °C

3: KOH, KCl, 27percent H₂O₂ / 20 °C

With hydrogenchloride; potassium hydroxide; methanesulfonic acid; potassium chloride; dihydrogen peroxide; hydroxylamine sulfate; sodium sulfate; In water;
DOI:10.1021/jm00105a034

Reference yield:

: 129833-52-9
N-(3-bromo-2-methylphenyl)-2-hydroxyiminoacetamide

: 129833-29-0
2-amino-4-bromo-3-methylbenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: CH₃SO₃H / 70 - 80 °C

2: KOH, KCl, 27percent H₂O₂ / 20 °C

With potassium hydroxide; methanesulfonic acid; potassium chloride; dihydrogen peroxide;
DOI:10.1021/jm00105a034