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Selank peptide

Base Information Edit
  • Chemical Name:Selank peptide
  • CAS No.:129954-34-3
  • Molecular Formula:C33H57N11O9
  • Molecular Weight:0.00000
  • Hs Code.:
  • DSSTox Substance ID:DTXSID701029276
  • Wikipedia:Selank
  • Mol file:129954-34-3.mol
Selank peptide

Synonyms:Selank;Thr-Lys-Pro-Arg-Pro-Gly-Pro;threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline;TP 7;TP-7

Suppliers and Price of Selank peptide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Cayman Chemical
  • Selank (acetate)
  • 5mg
  • $ 469.00
  • Cayman Chemical
  • Selank (acetate)
  • 1mg
  • $ 125.00
Total 93 raw suppliers
Chemical Property of Selank peptide Edit
Chemical Property:
  • Melting Point:134-136 °C 
  • PKA:3.43±0.20(Predicted) 
  • PSA:0.00000 
  • Density:1.53±0.1 g/cm3(Predicted) 
  • LogP:0.00000 
  • XLogP3:-6.1
  • Hydrogen Bond Donor Count:9
  • Hydrogen Bond Acceptor Count:12
  • Rotatable Bond Count:19
  • Exact Mass:751.43407244
  • Heavy Atom Count:53
  • Complexity:1360
Purity/Quality:

99.9% *data from raw suppliers

Selank (acetate) *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:CC(C(C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)N2CCCC2C(=O)NCC(=O)N3CCCC3C(=O)O)N)O
  • Isomeric SMILES:C[C@H]([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)NCC(=O)N3CCC[C@H]3C(=O)O)N)O
  • Description Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg.
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