Technology Process of 2-N-methylamino-1,3-di(4-methylthiophenyl)propane
There total 5 articles about 2-N-methylamino-1,3-di(4-methylthiophenyl)propane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium fluoride; N,N-dimethylammonium chloride / toluene / 24 h / Reflux
2: iron; acetic acid / 2 h / 100 °C
3: formic acid / 7 h / 150 °C
4: hydrogenchloride; water / methanol / 7 h / Reflux
With
hydrogenchloride; potassium fluoride; formic acid; water; N,N-dimethylammonium chloride; iron; acetic acid;
In
methanol; toluene;
1: Henry reaction;
DOI:10.1016/j.bmc.2010.11.054
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium tetrahydroborate; silica gel / dichloromethane; isopropyl alcohol / 0.33 h / 20 °C
2: potassium fluoride; N,N-dimethylammonium chloride / toluene / 24 h / Reflux
3: iron; acetic acid / 2 h / 100 °C
4: formic acid / 7 h / 150 °C
5: hydrogenchloride; water / methanol / 7 h / Reflux
With
hydrogenchloride; potassium fluoride; sodium tetrahydroborate; formic acid; water; N,N-dimethylammonium chloride; silica gel; iron; acetic acid;
In
methanol; dichloromethane; isopropyl alcohol; toluene;
2: Henry reaction;
DOI:10.1016/j.bmc.2010.11.054
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iron; acetic acid / 2 h / 100 °C
2: formic acid / 7 h / 150 °C
3: hydrogenchloride; water / methanol / 7 h / Reflux
With
hydrogenchloride; formic acid; water; iron; acetic acid;
In
methanol;
DOI:10.1016/j.bmc.2010.11.054
