2,2,3-trifluorosuccinic acid

Base Information

Chemical Name:2,2,3-trifluorosuccinic acid
CAS No.:28812-58-0
Molecular Formula:C₄H₃F₃O₄
Molecular Weight:172.061
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,2,3-trifluorosuccinic acid

Chemical Property:

Purity/Quality:

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Technology Process of 2,2,3-trifluorosuccinic acid

There total 4 articles about 2,2,3-trifluorosuccinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 866-16-0
chloro-trifluoro-succinic acid

: 664-66-4,28812-58-0
2,2,3-trifluorosuccinic acid

Guidance literature:: With zinc;
DOI:10.1021/jp984554o

Reference yield:

concentrated H₂ SO₄: concentrated H₂ SO₄

: 866-16-0
chloro-trifluoro-succinic acid

: 664-66-4,28812-58-0
2,2,3-trifluorosuccinic acid

Guidance literature:: In 1,4-dioxane; water;

Reference yield:

: 108-31-6
maleic anhydride

: 664-66-4,28812-58-0
2,2,3-trifluorosuccinic acid

: 74398-82-6
meso-α,α'-difluorosuccinic acid

: DL-α,α'-difluorosuccinic acid

: 2,3-difluorobut-2-enoic acid

: threo-2-chloro-3-fluorosuccinic acid

: erythro-2-chloro-3-fluorosuccinic acid

Guidance literature:: With sulfuric acid; fluorine; sodium fluoride; Product distribution; 1.) CHCl₃, -25 deg C, 2.) H₂O; other solvent and temperature, other acid products (identified as corresponding dimethyl esters);
DOI:10.1016/0022-1139(93)02975-K