2,2a(2)-Oxybis[5-(trifluoromethyl)benzenamine]

Base Information

Chemical Name:2,2a(2)-Oxybis[5-(trifluoromethyl)benzenamine]
CAS No.:349-15-5
Molecular Formula:C₁₄H₁₀F₆N₂O
Molecular Weight:336.237
Hs Code.:
DSSTox Substance ID:DTXSID101262779

Synonyms:SCHEMBL8935331;VNDSUOVJYAWFLT-UHFFFAOYSA-N;DTXSID101262779;2,2a(2)-Oxybis[5-(trifluoromethyl)benzenamine];2-[2-amino-4-(trifluoromethyl)phenoxy]-5-(trifluoromethyl)aniline;349-15-5

Suppliers and Price of 2,2a(2)-Oxybis[5-(trifluoromethyl)benzenamine]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,2a(2)-Oxybis[5-(trifluoromethyl)benzenamine]

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:2
Exact Mass:336.06973192
Heavy Atom Count:23
Complexity:364

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(F)(F)F)N)OC2=C(C=C(C=C2)C(F)(F)F)N

Technology Process of 2,2a(2)-Oxybis[5-(trifluoromethyl)benzenamine]

There total 3 articles about 2,2a(2)-Oxybis[5-(trifluoromethyl)benzenamine] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 346-41-8
bis-(2-nitro-4-trifluoromethyl-phenyl)-ether

: 349-15-5
bis-(2-amino-4-trifluoromethyl-phenyl)-ether

Guidance literature:: With tin(ll) chloride;
DOI:10.1021/ja01604a022

Reference yield:

: 121-17-5
2-chloro-3-nitro-5-trifluoromethylbenzene

: 349-15-5
bis-(2-amino-4-trifluoromethyl-phenyl)-ether

Guidance literature:: Multi-step reaction with 2 steps

1: KF; DMF; H₂O / 160 °C

2: SnCl₂

With potassium fluoride; water; N,N-dimethyl-formamide; tin(ll) chloride;
DOI:10.1021/ja01604a022