3-[4-(Trifluoromethyl)phenyl]thiophene

Base Information

Chemical Name:3-[4-(Trifluoromethyl)phenyl]thiophene
CAS No.:122159-58-4
Molecular Formula:C₁₁H₇F₃S
Molecular Weight:228.238
Hs Code.:
DSSTox Substance ID:DTXSID40924099
Nikkaji Number:J1.376.045D
Wikidata:Q82898238
Mol file:122159-58-4.mol

Synonyms:3-[4-(trifluoromethyl)phenyl]thiophene;122159-58-4;3-(4-Trifluoromethyl-phenyl)-thiophene;3-(4-(Trifluoromethyl)phenyl)thiophene;SCHEMBL2289309;DTXSID40924099;3-(4-trifluoromethylphenyl)-thiophene;AKOS004118777;BB 0223672;122159-17-5

Suppliers and Price of 3-[4-(Trifluoromethyl)phenyl]thiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(4-TRIFLUOROMETHYL-PHENYL)-THIOPHENE 95.00%
5MG
$ 501.20

Total 2 raw suppliers

Chemical Property of 3-[4-(Trifluoromethyl)phenyl]thiophene

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:228.02205588
Heavy Atom Count:15
Complexity:206

Purity/Quality:

99% ^*data from raw suppliers

3-(4-TRIFLUOROMETHYL-PHENYL)-THIOPHENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CSC=C2)C(F)(F)F

Technology Process of 3-[4-(Trifluoromethyl)phenyl]thiophene

There total 6 articles about 3-[4-(Trifluoromethyl)phenyl]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 10486-61-0
3-thienyl iodide

: 128796-39-4
4-trifluoromethylphenylboronic acid

: 122159-17-5,122159-58-4
3-(p-(trifluoromethyl)phenyl)thiophene

Guidance literature:: With potassium carbonate; In water; acetone; at 60 ℃; for 5h;
DOI:10.1002/ejoc.201000671

Reference yield: 65.0%

: 6165-69-1
Thien-3-ylboronic acid

: 1-(4-(trifluoromethyl)benzoyl)piperidine-2,6-dione

: 122159-17-5,122159-58-4
3-(p-(trifluoromethyl)phenyl)thiophene

Guidance literature:: With bis(tricyclohexylphosphine)nickel(II) dichloride; sodium carbonate; In 1,4-dioxane; at 150 ℃; for 12h; Schlenk technique; Inert atmosphere;
DOI:10.1002/anie.201601914

Reference yield:

: 872-31-1
3-Bromothiophene

: 128796-39-4
4-trifluoromethylphenylboronic acid

: 122159-17-5,122159-58-4
3-(p-(trifluoromethyl)phenyl)thiophene

Guidance literature:: With tetra-(n-butyl)ammonium iodide; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 87 ℃; for 48h;