Technology Process of (2Z,4E,6E,8E)-7-Methyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenenitrile
There total 4 articles about (2Z,4E,6E,8E)-7-Methyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenenitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 79 percent / activated MnO2 / petroleum ether
2: 1.) sodium hydride / 1.) THF, 0 - 20 deg C, 20 min, 2.) ice-bath temperature to room temperature, 30 min
With
manganese(IV) oxide; sodium hydride;
In
Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) BuLi / 1.) -30 deg C, THF, hexane, 30 min, 2.) THF, hexane, -60 deg C to room temperature
2: 87 percent / LiAlH4 / tetrahydrofuran / 1. a) 10 min, 0 deg C, b) 3 h, reflux
3: 79 percent / activated MnO2 / petroleum ether
4: 1.) sodium hydride / 1.) THF, 0 - 20 deg C, 20 min, 2.) ice-bath temperature to room temperature, 30 min
With
manganese(IV) oxide; lithium aluminium tetrahydride; n-butyllithium; sodium hydride;
In
tetrahydrofuran; Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 87 percent / LiAlH4 / tetrahydrofuran / 1. a) 10 min, 0 deg C, b) 3 h, reflux
2: 79 percent / activated MnO2 / petroleum ether
3: 1.) sodium hydride / 1.) THF, 0 - 20 deg C, 20 min, 2.) ice-bath temperature to room temperature, 30 min
With
manganese(IV) oxide; lithium aluminium tetrahydride; sodium hydride;
In
tetrahydrofuran; Petroleum ether;
