6-Methoxyquinoline-3-carbonitrile

Base Information

Chemical Name:6-Methoxyquinoline-3-carbonitrile
CAS No.:13669-58-4
Molecular Formula:C₁₁H₈N₂O
Molecular Weight:184.197
Hs Code.:
DSSTox Substance ID:DTXSID801299474
Mol file:13669-58-4.mol

Synonyms:6-METHOXYQUINOLINE-3-CARBONITRILE;13669-58-4;6-methoxy-3-quinolinecarbonitrile;3-Quinolinecarbonitrile, 6-methoxy-;SCHEMBL6990269;IWDUVIPVMFJQJF-UHFFFAOYSA-N;DTXSID801299474;AMY26358;MFCD22628175;AKOS022970867;SB68596;AS-42843;DB-399684;CS-0098332

Suppliers and Price of 6-Methoxyquinoline-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Methoxyquinoline-3-carbonitrile 95+%
1g
$ 1148.00

Chemenu
6-Methoxyquinoline-3-carbonitrile 95%
1g
$ 1082.00

Alichem
6-Methoxyquinoline-3-carbonitrile
250mg
$ 396.00

Total 8 raw suppliers

Chemical Property of 6-Methoxyquinoline-3-carbonitrile

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:184.063662883
Heavy Atom Count:14
Complexity:245

Purity/Quality:

97% ^*data from raw suppliers

6-Methoxyquinoline-3-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=CC(=CN=C2C=C1)C#N

Technology Process of 6-Methoxyquinoline-3-carbonitrile

There total 6 articles about 6-Methoxyquinoline-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 288-14-2
ISOXAZOLE

: 26831-52-7
2-amino-5-methoxybenzaldehyde

: 13669-58-4
6-methoxyquinoline-3-carbonitrile

Guidance literature:: With [RuCl₂pentamethylcyclopentadiene]_n; silver trifluoroacetate; trifluoroacetic acid; In 2,2,2-trifluoroethanol; at 80 ℃; for 8h;

Reference yield: 17.0%

: 2-azidomethyl-3-(3-methoxyphenyl)acrylonitrile

: 5-bromo-8-methoxyquinoline-3-carbonitrile

: 5-bromo-6-methoxyquinoline-3-carbonitrile

: 13669-58-4
6-methoxyquinoline-3-carbonitrile

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at 20 ℃; regioselective reaction; Inert atmosphere; Irradiation; Sealed tube;
DOI:10.1002/adsc.201400637

Reference yield:

: 3-hydroxy-3-(3-methoxyphenyl)-2-methylenepropionitrile

: 5-bromo-8-methoxyquinoline-3-carbonitrile

: 5-bromo-6-methoxyquinoline-3-carbonitrile

: 13669-58-4
6-methoxyquinoline-3-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: dmap / dichloromethane / 1 h / 20 °C

2: sodium azide / tetrahydrofuran; water / 20 °C

3: N-Bromosuccinimide / dichloromethane / 20 °C / Inert atmosphere; Irradiation; Sealed tube

With dmap; N-Bromosuccinimide; sodium azide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/adsc.201400637