1-(2-(Methylthio)phenyl)propan-1-one

Base Information

Chemical Name:1-(2-(Methylthio)phenyl)propan-1-one
CAS No.:133101-41-4
Molecular Formula:C₁₀H₁₂OS
Molecular Weight:180.271
Hs Code.:
DSSTox Substance ID:DTXSID301290465

Synonyms:1-(2-(Methylthio)phenyl)propan-1-one;133101-41-4;1-[2-(methylsulfanyl)phenyl]propan-1-one;SCHEMBL5664606;DTXSID301290465;1-[2-(Methylthio)phenyl]-1-propanone;1-(2-Methylsulfanyl-phenyl)-propan-1-one

Suppliers and Price of 1-(2-(Methylthio)phenyl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1-(2-(Methylthio)phenyl)propan-1-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:180.06088618
Heavy Atom Count:12
Complexity:156

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(=O)C1=CC=CC=C1SC

Technology Process of 1-(2-(Methylthio)phenyl)propan-1-one

There total 2 articles about 1-(2-(Methylthio)phenyl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30439-32-8
1-(2-Methylsulfanyl-phenyl)-propan-1-ol

: 133101-41-4
1-<2-(methylthio)phenyl>-1-propanone

Guidance literature:: With Celite; pyridinium chlorochromate; In dichloromethane; Yield given; Ambient temperature;
DOI:10.1021/jo00009a030

Reference yield:

: 7022-45-9
2-(methylsulfanyl)benzaldehyde

: 133101-41-4
1-<2-(methylthio)phenyl>-1-propanone

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 2 h / -20 °C

2: pyridinium chlorochromate (PPC), celite / CH₂Cl₂ / Ambient temperature

With Celite; pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jo00009a030

Reference yield:

: 133101-41-4
1-<2-(methylthio)phenyl>-1-propanone

: 133101-61-8,133127-84-1
trans-(RR,SS)-γ-hydroxy-β-methyl-γ-<2-(methylthio)phenyl>butanoic acid lactone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) potassium hexamethyldisilazide (KHMDS) / 1.) toluene, THF, -78 deg C, 1 h, 2.) -78 deg C, 1 h

2: 2N NaOH / tetrahydrofuran; methanol / 2 h / Ambient temperature

3: 1.) diisobutylaluminiumhydride (DIBAL-H), ZnCl₂, 2.) 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide methyl p-toluenesulfonate, 4-(dimethylamino)pyridine / 1.) THF, toluene, -78 deg C, 3 h, 2.) CH₂Cl₂, THF, RT, 18 h

With dmap; sodium hydroxide; 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide methyl toluene-p-sulphonate; potassium hexamethylsilazane; diisobutylaluminium hydride; zinc(II) chloride; In tetrahydrofuran; methanol;
DOI:10.1021/jo00009a030