O-benzyl-L-serine

Base Information

• Chemical Name: O-benzyl-L-serine
• CAS No.: 52161-82-7
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.218
• Mol file: 52161-82-7.mol

Synonyms:

Chemical Property of O-benzyl-L-serine

Chemical Property:

• Melting Point: 241-242 °C (decomp)
• Boiling Point: 394.1±37.0 °C(Predicted)
• Density: 1?+-.0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

O-Phenyl-L-homoserine 97%,ee98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-benzyl-L-serine

There total 1 articles about O-benzyl-L-serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ O-benzyl-L-serine (52161-82-7)

Guidance literature:

DOI:10.1021/ja01185a025

Reference yield:

O-benzyl-L-serine (52161-82-7) → (4S)-4-[(benzyloxy)methyl]-1,3-oxazolidin-2-one (158612-99-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 48 percent / BH₃ / tetrahydrofuran

2: 76 percent / CH₂Cl₂

With borane; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(00)01301-0

Reference yield:

O-benzyl-L-serine (52161-82-7) → (S)-4-benzyloxymethyl-2-oxo-oxazolidine-3-carboxylic acid tert-butyl ester (312736-43-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 48 percent / BH₃ / tetrahydrofuran

2: 76 percent / CH₂Cl₂

3: 87 percent / DMAP / CH₂Cl₂

With dmap; borane; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(00)01301-0

Downstream raw materials:

(4S)-4-[(benzyloxy)methyl]-1,3-oxazolidin-2-one

(S)-4-benzyloxymethyl-2-oxo-oxazolidine-3-carboxylic acid tert-butyl ester