17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid

Base Information

• Chemical Name: 17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid
• CAS No.: 122650-82-2
• Molecular Formula: C₂₆H₄₀O₆
• Molecular Weight: 448.6
• Mol file: 122650-82-2.mol

Synonyms:

Chemical Property of 17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid

There total 2 articles about 17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid (122650-82-2)

Guidance literature:

With chromium(VI) oxide; acetic acid;

DOI:10.1021/ja01215a001 DOI:10.1021/ja01202a048

Reference yield:

17β-cyclohexanecarbonyloxy-5α-androstan-3-one (20592-38-5) → 17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid (122650-82-2)

Guidance literature:

With chromium(VI) oxide; acetic acid;

Reference yield:

17β-cyclohexanecarbonyloxy-2,3-seco-5α-androstane-2,3-dioic acid (122650-82-2) → 17β-Hydroxy-17α-methyl-A-nor-5α-androstan-2-on (2240-02-0)

Guidance literature:

Multi-step reaction with 7 steps

1: Hydrolysis

2: Erhitzen des Reaktionsprodukts unter 10 Torr auf 240grad

3: benzene; toluene-4-sulfonic acid

4: methanol. KOH-solution

5: chromium (VI)-oxide; pyridine

6: diethyl ether

7: toluene-4-sulfonic acid; acetone

With pyridine; chromium(VI) oxide; potassium hydroxide; diethyl ether; toluene-4-sulfonic acid; acetone; benzene;

upstream raw materials:

17β-cyclohexanecarbonyloxy-5α-androstan-3-one

Downstream raw materials:

17β-Hydroxy-17α-methyl-A-nor-5α-androstan-2-on