C₁₀H₁₂N₂O₃

Base Information

• Chemical Name: C₁₀H₁₂N₂O₃
• CAS No.: 104412-23-9
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.217
• Mol file: 104412-23-9.mol

Synonyms:

Chemical Property of C₁₀H₁₂N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₁₂N₂O₃

There total 3 articles about C₁₀H₁₂N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2,3-dimethylphenyl)glycine (83442-59-5) → C10H12N2O3 (104412-23-9)

Guidance literature:

With hydrogenchloride; sodium nitrite; at 0 - 5 ℃; for 4h;

Reference yield:

2,3-Dimethylaniline (87-59-2) → C10H12N2O3 (104412-23-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 57 percent / ethanol; H₂O / 3 h / Heating

2.1: NaNO₂; aq. NaOH

2.2: aq. HCl

With sodium hydroxide; sodium nitrite; In ethanol; water;

Reference yield:

N-<2,3-Dimethyl-phenyl>-glycin-aethylester (2345-06-4) → C10H12N2O3 (104412-23-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 10percent aq. NaOH / ethanol / 0.5 h / Heating

2: NaNO₂/12percent aq. HCl / 4 h / 0 - 5 °C

With hydrogenchloride; sodium hydroxide; sodium nitrite; In ethanol;

upstream raw materials:

N-(2,3-dimethylphenyl)glycine

2,3-Dimethylaniline

N-<2,3-Dimethyl-phenyl>-glycin-aethylester

Downstream raw materials:

3-(2,3-dimethylphenyl)sydnone

Refernces

• 1、 Turnbull, Kenneth. "Bromination of Sydnones. I. Reaction with 3-Arylsydnones Containing Electron-Donors on the Aryl Ring". . p. 965 - 968. Retrieved 2007/10/02.