2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride

Base Information

• Chemical Name: 2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride
• CAS No.: 113487-74-4
• Molecular Formula: C₂₆H₂₄O₁₀
• Molecular Weight: 496.471
• Mol file: 113487-74-4.mol

Synonyms:

Chemical Property of 2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride

There total 3 articles about 2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

4'-hydroxy-3'-methoxycarbonylphenyl 2-hydroxy-4-methoxy-6-methylbenzoate (113487-70-0) → 2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride (113487-74-4)

Guidance literature:

With lithium carbonate; In dimethyl sulfoxide; for 24h;

DOI:10.1071/CH9871451

Reference yield:

2-benzyloxy-4-methoxy-6-methylbenzoic acid (68048-09-9) → 2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride (113487-74-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / trifluoroacid anhydride / toluene / 2 h / Ambient temperature

2: 94 percent / H₂ / 10percent Pd/C / ethyl acetate / 16 h

3: 9 percent / lithium carbonate / dimethylsulfoxide / 24 h

With trifluoroacid anhydride; hydrogen; lithium carbonate; palladium on activated charcoal; In dimethyl sulfoxide; ethyl acetate; toluene;

DOI:10.1071/CH9871451

Reference yield:

4'-hydroxy-3'-methoxycarbonylphenyl 2-benzyloxy-4-methoxy-6-methylbenzoate (113487-68-6) → 2''-hydroxy-4''-methoxy-6''-methylbenzoic 2-(4'-hydroxy-3'-methoxycarbonylphenoxy)-4-methoxy-6-methylbenzoic anhydride (113487-74-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / H₂ / 10percent Pd/C / ethyl acetate / 16 h

2: 9 percent / lithium carbonate / dimethylsulfoxide / 24 h

With hydrogen; lithium carbonate; palladium on activated charcoal; In dimethyl sulfoxide; ethyl acetate;

DOI:10.1071/CH9871451

upstream raw materials:

4'-hydroxy-3'-methoxycarbonylphenyl 2-hydroxy-4-methoxy-6-methylbenzoate

2-benzyloxy-4-methoxy-6-methylbenzoic acid

4'-hydroxy-3'-methoxycarbonylphenyl 2-benzyloxy-4-methoxy-6-methylbenzoate

Refernces