3(R)-<amino>-2-oxo-1-pyrrolidineacetamide

Base Information

Chemical Name:3(R)-<amino>-2-oxo-1-pyrrolidineacetamide
CAS No.:114200-41-8
Molecular Formula:C₁₉H₂₄N₄O₅
Molecular Weight:388.423
Hs Code.:

3(R)-<<N-(benzyloxycarbonyl)-L-prolyl>amino>-2-oxo-1-pyrrolidineacetamide

Synonyms:

Suppliers and Price of 3(R)-<amino>-2-oxo-1-pyrrolidineacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3(R)-<amino>-2-oxo-1-pyrrolidineacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3(R)-<amino>-2-oxo-1-pyrrolidineacetamide

There total 5 articles about 3(R)-<amino>-2-oxo-1-pyrrolidineacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-2-((R)-1-Methoxycarbonylmethyl-2-oxo-pyrrolidin-3-ylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester

: 114200-41-8
3(R)-<amino>-2-oxo-1-pyrrolidineacetamide

Guidance literature:: With ammonia; In methanol; for 12h; Yield given; Ambient temperature;
DOI:10.1021/jm00402a031

Reference yield:

: 78444-90-3,116339-45-8
(R)-3-<(tert-butyloxycarbonyl)amino>-2-oxo-1-pyrrolidineacetic acid

: 114200-41-8
3(R)-<amino>-2-oxo-1-pyrrolidineacetamide

Guidance literature:: Multi-step reaction with 4 steps

1: methanol; diethyl ether / 2 h / Ambient temperature

2: aq. HCl / dioxane / 0.33 h / 0 °C

3: diphenyl phosphorazidate, Et₃N / dimethylformamide / 1) 0 deg C, 2 d; 2) room temperature, overnight

4: NH₃ / methanol / 12 h / Ambient temperature

With hydrogenchloride; diphenyl phosphoryl azide; ammonia; triethylamine; In 1,4-dioxane; methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm00402a031

Reference yield:

: 783303-33-3
((R)-3-Amino-2-oxo-pyrrolidin-1-yl)-acetic acid methyl ester

: 114200-41-8
3(R)-<amino>-2-oxo-1-pyrrolidineacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: diphenyl phosphorazidate, Et₃N / dimethylformamide / 1) 0 deg C, 2 d; 2) room temperature, overnight

2: NH₃ / methanol / 12 h / Ambient temperature

With diphenyl phosphoryl azide; ammonia; triethylamine; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00402a031