1H-Pyrazole-4,5-diamine, 1-(phenylmethyl)-

Base Information

Chemical Name:1H-Pyrazole-4,5-diamine, 1-(phenylmethyl)-
CAS No.:131311-66-5
Molecular Formula:C10H12N4
Molecular Weight:188.232
Hs Code.:
DSSTox Substance ID:DTXSID70456999
Nikkaji Number:J1.518.208C
Wikidata:Q82279659

Synonyms:2-benzylpyrazole-3,4-diamine;131311-66-5;1H-Pyrazole-4,5-diamine, 1-(phenylmethyl)-;1-Benzyl-1H-pyrazole-4,5-diamine;SCHEMBL144813;DTXSID70456999;AKOS017529965;FT-0718591

Suppliers and Price of 1H-Pyrazole-4,5-diamine, 1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Pyrazole-4,5-diamine, 1-(phenylmethyl)-

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:188.106196400
Heavy Atom Count:14
Complexity:179

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C(=C(C=N2)N)N

Technology Process of 1H-Pyrazole-4,5-diamine, 1-(phenylmethyl)-

There total 7 articles about 1H-Pyrazole-4,5-diamine, 1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-benzylamino-1-benzyl-3-bromo-4-nitropyrazole

: 131311-66-5
4,5-diamino-1-(phenylmethyl)-1H-pyrazole

Guidance literature:: With sulfuric acid; pyrographite; In ethanol;

Reference yield:

: 716379-29-2
(5-amino-1-benzyl-1H-pyrazol-4-yl)-carbamic acid benzyl ester

: 131311-66-5
4,5-diamino-1-(phenylmethyl)-1H-pyrazole

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 1.5h;
DOI:10.1016/j.tetlet.2004.03.142

Reference yield:

: 19867-62-0
ethyl 5-amino-1-benzyl-1H-pyrazole-4-carboxylate

: 131311-66-5
4,5-diamino-1-(phenylmethyl)-1H-pyrazole

Guidance literature:: Multi-step reaction with 4 steps

1: 73 percent / hydrazine monohydrate / ethanol / Heating

2: 82 percent / NaNO₂; acetic acid / H₂O / 0.5 h / 0 °C

3: 71 percent / xylene / Heating

4: H₂ / Pd/C / methanol / 1.5 h / 20 °C

With hydrogen; hydrazine hydrate; acetic acid; sodium nitrite; palladium on activated charcoal; In methanol; ethanol; water; xylene; 3: Curtius rearrangement;
DOI:10.1016/j.tetlet.2004.03.142