Epinephrine Sulfate

Base Information

• Chemical Name: Epinephrine Sulfate
• CAS No.: 21093-18-5
• Molecular Formula: C₉H₁₃NO₆S
• Molecular Weight: 263.271
• Mol file: 21093-18-5.mol

Synonyms:

Chemical Property of Epinephrine Sulfate

Chemical Property:

• Melting Point: >170°C (dec.)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

Epinephrine4-O-SulfateEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Epinephrine (E588585) derivative.

Technology Process of Epinephrine Sulfate

There total 2 articles about Epinephrine Sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

adrenalone-4-O-sulfate (80098-06-2) → dl-epinephrine-4-O-sulfate (21093-18-5)

Guidance literature:

With sodium tetrahydroborate; In methanol; isopropyl alcohol; for 7h; Yield given;

DOI:10.1248/cpb.29.2086

Reference yield:

adrenalone (99-45-6) → dl-epinephrine-4-O-sulfate (21093-18-5)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfonic acid / 1 h / -45 - -2 °C

2: NaBH₄ / methanol; propan-2-ol / 7 h

With chlorosulfonic acid; sodium tetrahydroborate; In methanol; isopropyl alcohol;

DOI:10.1248/cpb.29.2086

upstream raw materials:

adrenalone-4-O-sulfate

adrenalone

Refernces