5-(1,3-Benzodioxol-5-yl)-8a,9-dihydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8h)-one

Base Information

Chemical Name:5-(1,3-Benzodioxol-5-yl)-8a,9-dihydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8h)-one
CAS No.:81410-42-6
Molecular Formula:C₂₀H₁₄O₆
Molecular Weight:350.328
Hs Code.:
NSC Number:112137
DSSTox Substance ID:DTXSID60296846
Nikkaji Number:J3.289.433J
Wikidata:Q82037635

Synonyms:81410-42-6;5-(1,3-benzodioxol-5-yl)-8a,9-dihydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8h)-one;NSC112137;DTXSID60296846;NSC-112137

Suppliers and Price of 5-(1,3-Benzodioxol-5-yl)-8a,9-dihydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8h)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 5-(1,3-Benzodioxol-5-yl)-8a,9-dihydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8h)-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:350.07903816
Heavy Atom Count:26
Complexity:644

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2COC(=O)C2=C(C3=CC4=C(C=C31)OCO4)C5=CC6=C(C=C5)OCO6

Technology Process of 5-(1,3-Benzodioxol-5-yl)-8a,9-dihydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8h)-one

There total 5 articles about 5-(1,3-Benzodioxol-5-yl)-8a,9-dihydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8h)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71616-32-5
(E)-3-(benzo[d][1,3]dioxol-5-yl)allyl 3-(benzo[d][1,3]dioxol-5-yl)propiolate

: 14944-34-4
3-hydroxymethyl-6,7-methylenedioxy-1-(3,4-methylenedioxyphenyl)naphthalene-2-carboxylic acid lactone

: 81410-42-6
3,4-dihydro-3-hydroxymethyl-6,7-methylenedioxy-1-(3,4-methylenedioxyphenyl)naphthalene-2-carboxylic acid lactone

Guidance literature:: With acetic anhydride; at 140 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.tetlet.2013.12.014

Reference yield:

: 31893-02-4
3-(benzo[d][1,3]dioxol-5-yl)propionic acid methyl ester

: 14944-34-4
3-hydroxymethyl-6,7-methylenedioxy-1-(3,4-methylenedioxyphenyl)naphthalene-2-carboxylic acid lactone

: 81410-42-6
3,4-dihydro-3-hydroxymethyl-6,7-methylenedioxy-1-(3,4-methylenedioxyphenyl)naphthalene-2-carboxylic acid lactone

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / ethanol / 20 °C

2: dicyclohexyl-carbodiimide; dmap / dichloromethane / 0 - 20 °C

3: acetic anhydride / 12 h / 140 °C / Inert atmosphere

With dmap; acetic anhydride; potassium carbonate; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; 3: |Diels-Alder Cycloaddition;
DOI:10.1016/j.tetlet.2013.12.014

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 14944-34-4
3-hydroxymethyl-6,7-methylenedioxy-1-(3,4-methylenedioxyphenyl)naphthalene-2-carboxylic acid lactone

: 81410-42-6
3,4-dihydro-3-hydroxymethyl-6,7-methylenedioxy-1-(3,4-methylenedioxyphenyl)naphthalene-2-carboxylic acid lactone

Guidance literature:: Multi-step reaction with 5 steps

1.1: triphenylphosphine / dichloromethane / 20 °C

2.1: n-butyllithium / tetrahydrofuran / -78 °C

2.2: -78 - 20 °C

3.1: potassium carbonate / ethanol / 20 °C

4.1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 0 - 20 °C

5.1: acetic anhydride / 12 h / 140 °C / Inert atmosphere

With dmap; n-butyllithium; acetic anhydride; potassium carbonate; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran; ethanol; dichloromethane; 2.1: |Corey-Fuchs Alkyne Synthesis / 2.2: |Corey-Fuchs Alkyne Synthesis / 5.1: |Diels-Alder Cycloaddition;
DOI:10.1016/j.tetlet.2013.12.014