2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Base Information

Chemical Name:2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one
CAS No.:13165-11-2
Molecular Formula:C14H11ClN2O
Molecular Weight:258.707
Hs Code.:
European Community (EC) Number:653-899-2
DSSTox Substance ID:DTXSID20384536
Nikkaji Number:J1.854.974C
Pharos Ligand ID:NWFKNY86VUDD
ChEMBL ID:CHEMBL1448672

Synonyms:13165-11-2;2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one;2-(4-chlorophenyl)-1,2,3,4-tetrahydroquinazolin-4-one;BAS 00699730;2-(4-chlorophenyl)-2,3-dihydro-1H-quinazolin-4-one;Oprea1_047265;Oprea1_107852;MLS000712808;SCHEMBL257093;CHEMBL1448672;DTXSID20384536;FPWIEUZTQYJRJZ-UHFFFAOYSA-N;BDBM150782;HMS1676P06;HMS2692A23;STK826067;AKOS000544721;CCG-242491;SMR000282575;CS-0299711;EN300-25293049;BRD-A39576036-001-07-4;Z48978323;1,2-Dihydro-2-(4-chlorophenyl)quinazoline-4(3H)-one;2-(4-Chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one (1e);2-(4-CHLOROPHENYL)-1,2-DIHYDRO-4(3H)-QUINAZOLINONE

Suppliers and Price of 2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:258.0559907
Heavy Atom Count:18
Complexity:315

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)NC(N2)C3=CC=C(C=C3)Cl

Technology Process of 2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

There total 15 articles about 2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 104-88-1
4-chlorobenzaldehyde

: 28144-70-9,88-68-6
anthranilic acid amide

: 13165-11-2
2-(4-Chloro-phenyl)-2,3-dihydro-1H-quinazolin-4-one

Guidance literature:: With copper(II)-L-histidine on the surface Fe₃O₄ magnetic nanoparticle; In ethanol; at 80 ℃; for 0.416667h; Concentration; Reflux; Green chemistry;
DOI:10.1039/c6ra19776k

Reference yield: 98.0%

: 118-48-9
isatoic anhydride

: 104-88-1
4-chlorobenzaldehyde

: 13165-11-2
2-(4-Chloro-phenyl)-2,3-dihydro-1H-quinazolin-4-one

Guidance literature:: isatoic anhydride; With ammonium acetate; In neat (no solvent); at 100 ℃; Green chemistry;

4-chlorobenzaldehyde; With N,N,N’,N’-tetrabromobenzene-1,3-disulfonamide; In neat (no solvent); at 100 ℃; for 0.5h; Temperature; Green chemistry;
DOI:10.1007/s11164-016-2678-5

Reference yield: 98.0%

: 118-48-9
isatoic anhydride

: 631-61-8,92206-38-7
ammonium acetate

: 104-88-1
4-chlorobenzaldehyde

: 13165-11-2
2-(4-Chloro-phenyl)-2,3-dihydro-1H-quinazolin-4-one

Guidance literature:: With 3,3′-(butane-1,4-diyl)bis(1,2-dimethyl-1H-imidazole-3-ium) dibromide; for 0.0166667h; Microwave irradiation;
DOI:10.1134/S1070363215080265