(4-chloro-benzyl)-malonic acid diamide

Base Information

• Chemical Name: (4-chloro-benzyl)-malonic acid diamide
• CAS No.: 874533-16-1
• Molecular Formula: C₁₀H₁₁ClN₂O₂
• Molecular Weight: 226.663
• Mol file: 874533-16-1.mol

Synonyms:

Chemical Property of (4-chloro-benzyl)-malonic acid diamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-chloro-benzyl)-malonic acid diamide

There total 1 articles about (4-chloro-benzyl)-malonic acid diamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl (4-chlorobenzyl)malonate (37556-13-1) → (4-chloro-benzyl)-malonic acid diamide (874533-16-1)

Guidance literature:

With methanol; ammonia; sodium methylate;

DOI:10.1021/ja01133a529

Reference yield:

(4-chloro-benzyl)-malonic acid diamide (874533-16-1) → 4-chlorobenzylmalononitrile (2964-33-2)

Guidance literature:

With phosphorus pentoxide;

DOI:10.1021/ja01133a529

Reference yield:

(4-chloro-benzyl)-malonic acid diamide (874533-16-1) → 5-(4-chloro-benzyl)-pyrimidine-2,4,6-triyltriamine

Guidance literature:

Multi-step reaction with 2 steps

1: P₂O₅

2: sodium ethylate; ethanol

With ethanol; sodium ethanolate; phosphorus pentoxide;

DOI:10.1021/ja01133a529

upstream raw materials:

diethyl (4-chlorobenzyl)malonate

Downstream raw materials:

4-chlorobenzylmalononitrile