2-Ethynyl-4,5-dichlorobenzenamine

Base Information

Chemical Name:2-Ethynyl-4,5-dichlorobenzenamine
CAS No.:220185-64-8
Molecular Formula:C₈H₅Cl₂N
Molecular Weight:186.04
Hs Code.:
DSSTox Substance ID:DTXSID901298924
Nikkaji Number:J1.010.712A

Synonyms:4,5-dichloro-2-ethynylaniline;DTXSID901298924;2-Ethynyl-4,5-dichlorobenzenamine;4,5-Dichloro-2-ethynylbenzenamine;AKOS006308583;220185-64-8

Suppliers and Price of 2-Ethynyl-4,5-dichlorobenzenamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Ethynyl-4,5-dichlorobenzenamine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:184.9799046
Heavy Atom Count:11
Complexity:184

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C#CC1=CC(=C(C=C1N)Cl)Cl

Technology Process of 2-Ethynyl-4,5-dichlorobenzenamine

There total 4 articles about 2-Ethynyl-4,5-dichlorobenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₁H₁₃Cl₂NSi

: 220185-64-8
4,5-dichloro-2-ethynyl-phenylamine

Guidance literature:: With potassium carbonate; In methanol;
DOI:10.1016/j.molstruc.2020.129491

Reference yield:

: 220185-63-7
4,5-dichloro-2-iodobenzenamine

: 220185-64-8
4,5-dichloro-2-ethynyl-phenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: CuI, Et₃N, Cl₂Pd(PPh₃)2

2: NaOtBu / 2-methyl-propan-2-ol

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; sodium t-butanolate; In tert-butyl alcohol;
DOI:10.1016/S0040-4039(98)02161-3

Reference yield:

: 95-76-1
m,p-dichloroaniline

: 220185-64-8
4,5-dichloro-2-ethynyl-phenylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 59 percent / ICl / acetic acid

2: CuI, Et₃N, Cl₂Pd(PPh₃)2

3: NaOtBu / 2-methyl-propan-2-ol

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; Iodine monochloride; triethylamine; sodium t-butanolate; In acetic acid; tert-butyl alcohol;
DOI:10.1016/S0040-4039(98)02161-3