N-methyl-N-chloroformyl-p-aminotolane

Base Information

• Chemical Name: N-methyl-N-chloroformyl-p-aminotolane
• CAS No.: 129246-88-4
• Molecular Formula: C₁₆H₁₂ClNO
• Molecular Weight: 269.73
• Mol file: 129246-88-4.mol

Synonyms:

Chemical Property of N-methyl-N-chloroformyl-p-aminotolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methyl-N-chloroformyl-p-aminotolane

There total 2 articles about N-methyl-N-chloroformyl-p-aminotolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylacetylene (536-74-3) → N-methyl-N-chloroformyl-p-aminotolane (129246-88-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / Pd(PPh₃)2Cl₂, cuprous iodide, NEt₃ / 0.33 h / 60 °C

2: CCl₄ / acetonitrile / Irradiation

With tetrachloromethane; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In acetonitrile;

DOI:10.1007/BF00961695

Reference yield:

N,N-dimethyl-4-(phenylethynyl)aniline (14301-08-7) → α-phenyl-(4-N,N-dimethylamino)acetophenone (97606-39-8) + N-methyl-N-chloroformyl-p-aminotolane (129246-88-4) + (E)-p-dimethylamino-α-chlorostilbene (129246-87-3) + (Z)-p-dimethylamino-α-chlorostilbene (129246-89-5)

Guidance literature:

With tetrachloromethane; In acetonitrile; Yields of byproduct given; Irradiation;

DOI:10.1007/BF00961695

upstream raw materials:

N,N-dimethyl-4-(phenylethynyl)aniline

phenylacetylene