Cyclopentanone, 2-[(2-bromophenyl)methyl]-

Base Information

• Chemical Name: Cyclopentanone, 2-[(2-bromophenyl)methyl]-
• CAS No.: 132452-24-5
• Molecular Formula: C12H13BrO
• Molecular Weight: 253.139
• DSSTox Substance ID: DTXSID00438622
• Nikkaji Number: J893.469J
• Mol file: 132452-24-5.mol

Synonyms:Cyclopentanone, 2-[(2-bromophenyl)methyl]-;132452-24-5;SCHEMBL9296486;2-(2-Bromobenzyl)cyclopentanone;DTXSID00438622;IHJKRELWANHJRL-UHFFFAOYSA-N;AKOS010639727;2-[(2-bromophenyl)methyl]cyclopentanone

Chemical Property of Cyclopentanone, 2-[(2-bromophenyl)methyl]-

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 252.01498
• Heavy Atom Count: 14
• Complexity: 214

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C(=O)C1)CC2=CC=CC=C2Br

Technology Process of Cyclopentanone, 2-[(2-bromophenyl)methyl]-

There total 9 articles about Cyclopentanone, 2-[(2-bromophenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1-pyrrolidinocyclopent-1-ene (7148-07-4) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → 2-[(2-bromophenyl)methyl]cyclopentanone (132452-24-5)

Guidance literature:

With sodium iodide; In ethanol; for 4h; Heating;

DOI:10.1021/jo00089a009

Reference yield: 68.0%

cyclopentanone (120-92-3) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → 2-[(2-bromophenyl)methyl]cyclopentanone (132452-24-5)

Guidance literature:

cyclopentanone; With pyrrolidine; toluene-4-sulfonic acid; In benzene; for 3h; Heating;

1-Bromo-2-bromomethyl-benzene; In benzene; Heating;

With water; sodium acetate; acetic acid; In benzene; for 1h; Further stages.; Heating;

DOI:10.1021/ol015813m

Reference yield: 45.0%

1-Bromo-2-bromomethyl-benzene (3433-80-5) → 2-[(2-bromophenyl)methyl]cyclopentanone (132452-24-5)

Guidance literature:

In 1,4-dioxane;

upstream raw materials:

1-pyrrolidinocyclopent-1-ene

1-Bromo-2-bromomethyl-benzene

cyclopentanone

1-(N-morpholino)cyclopent-1-ene

Downstream raw materials:

2-benzyl-2-cyclopentenone

benzyl chloride

2-Benzyl-1-methylenecyclopentane

2-benzylcyclopentanone